智能三维脑血流成像系统与经颅多普勒诊断大脑中动脉狭窄对照研究  

A control study of intelligent 3D cerebral blood flow imaging system and TCD on diagnosing the stenosis of MCA

作　　者：宋欣昕 刘金苹[1] 王嘉 胡向东[1] 王艳红[1] 赵军凤[1] 刘玉江[1] 钱林学[1] SONG Xin-xin;LIU Jin-ping;WANG Jia(Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院超声科,北京100050

出　　处：《中国医学装备》2022年第10期67-70,共4页China Medical Equipment

基　　金：国家重点研发计划(2019YFC0121103)“智能三维脑血流成像系统对缺血性卒中患者颅内动脉狭窄AI筛查与CTA对照研究”。

摘　　要：目的:评估新型智能三维脑血流成像系统诊断颅内动脉病变与常规经颅多普勒(TCD)诊断结果的一致性,验证三维成像系统检查方法作为筛查颅内血管狭窄的有效手段。方法:在通过伦理学审查及中国临床试验中心注册后,选取医院神经内科脑血流图室就诊的57例脑血管病患者,使用三维脑血流成像系统共采集患者双侧114支大脑中动脉(MCA)的三维图像及血流频谱,评估三维成像系统采集成功率,根据测得血流频谱判断其狭窄情况,并与TCD诊断的狭窄结果进行对比,采用一致性检验评估三维成像系统与TCD诊断结果的一致性。结果:三维成像系统采集的114支MCA中采集成功93支,采集成功率为81.6%;三维成像系统诊断MCA无狭窄73支,TCD诊断MCA无狭窄71支;三维成像系统诊断MCA轻-中度狭窄12支,TCD诊断MCA轻-中度狭窄14支;三维成像系统诊断MCA重度狭窄-闭塞8支,TCD诊断MCA重度狭窄-闭塞8支;三维成像系统与TCD诊断MCA狭窄具有较好的一致性(Kappa=0.942,P<0.05)。结论:智能三维脑血流成像系统与TCD诊断一致性均在中等以上,在一定程度上可以作为MCA狭窄有效的筛查方法。Objective: To evaluate the diagnosis consistency of the 3D Imaging System and TCD in the diagnosis of intracranial blood artery(MCA). To demonstrate that the 3D Imaging System can become an effective screening method of intracranial vascular stenosis in a certain extent. Methods: After passing the examination of Ethic Committee and Chinese clinical trial registration, we selected eligible 57 cerebrovascular disease patients who received treatment in the Neurology Department. Through the 3D Imaging System, the 3D image and blood flow spectrum of bilateral 114 MCAs were gained. Then the success rate of 3D scanning as calculated. We compared the results of 3D Imaging System diagnosing with that of TCD, and evaluate their diagnostic efficiency through consistency test of 3D Imaging System examination and other examine methods. Results: 114 MCAs were examined from bilateral sides of subjects by 3D Imaging System, and 93 MCA were collected successfully. The success rate was 81.6%. There were 73 MCA without stenosis that diagnosed by the 3D imaging system, and 71 MCA without stenosis that diagnosed by TCD. There were 12 MCA with mild to moderate stenosis that diagnosed by the 3D imaging system, and 14 MCA with mild to moderate stenosis that diagnosed by TCD. There were 8 MCA with severe occlusion that diagnosed both by the 3D imaging system and by TCD. The 3D imaging system showed good consistency with TCD in the diagnosis of MCA stenosis, and the result was statistically significant(Kappa value=0.942, P<0.05). Conclusion: The diagnostic consistency of the new Intelligent 3D Cerebral Blood Flow Imaging System and TCD is above medium level, which makes the 3D Imaging System become an effective screening method for MCA stenosis to a certain extent.

关 键 词：智能三维脑血流超声成像系统 经颅多普勒(TCD) 大脑中动脉(MCA)狭窄 

分 类 号：R445.1[医药卫生—影像医学与核医学]