剖宫产产妇术前预防性应用抗生素对术后感染的影响及危险因素分析  

Effect of preoperative prophylactic use of antibiotics on postoperative infection and risk factors in cesarean section women

作　　者：沈敏雅 陆升华 陈瑜 SHEN Minya;LU Shenghua;CHEN Yu(Hangzhou Linping District First People's Hospital,Zhejiang 311100,China)

机构地区：[1]浙江省杭州市临平区第一人民医院,杭州311100

出　　处：《浙江创伤外科》2022年第5期827-829,共3页Zhejiang Journal of Traumatic Surgery

摘　　要：目的 探讨剖宫产产妇术前预防性应用抗生素对术后感染的影响。方法 选取杭州市临平区第一人民医院实施剖宫产手术的154例患者,分为观察组和对照组。观察两组临床情况及分析术后感染的影响因素。结果 观察组住院时间、体温恢复时间短于对照组,并发症发生率低于对照组,切口愈合情况优于对照组(P<0.05)。观察组术后感染率12.99%,低于对照组37.66%(P<0.05)。多因素分析显示,有阴道炎、胎膜早破、术中出血量≥500 mL、阴道检查次数≥4次、留置尿管时间长≥24 h、合并有糖尿病是影响剖宫产术后感染的独立危险因素。结论 剖宫产术使用抗生素时机对预防术后感染具有重要意义,术前0.5~1 h为最佳使用时间。此外,因积极留意影响因素是有效预防术后感染的重要手段。Objective To investigate the effect of preoperative prophylactic antibiotics on postoperative infection in cesarean section.Methods A total of 154 patients who underwent cesarean section in our hospital were selected and divided into observation group and control group.Observe the clinical situation of the two groups and analyze the influencing factors of postoperative infection. Results The hospitalization time and temperature recovery time of the observation group were shorter than those of the control group, the incidence of complications was lower than that of the control group, and the incision healing was better than that of the control group( P<0.05). The postoperative infection rate of the observation group was 12.99% lower than that of the control group 37.66%(P<0.05). Multivariate analysis showed that vaginitis, premature rupture of membranes, intra-operative blood loss>500mL, vaginal examination times>4 times, indwelling catheter time>24h, combined with diabetes were independent risk factors for infection after cesarean section. Conclusion Timing of antibiotic use in cesarean section has great significance for preventing postoperative in-fection. The best time of antibiotic use is 0.5~1h before cesarean section. In addition, active attention to influencing factors is an important means to effectively prevent postoperative infection.

关 键 词：剖宫产 抗生素 术后感染 影响因素 

分 类 号：R714.2[医药卫生—妇产科学]