联合注射治疗瘢痕疙瘩的临床现状  

Clinical Status of Combined Injection in the Treatment of Keloid

作　　者：朱学娥(综述) 丁媛(审校)[2] ZHU Xue’e;DING Yuan(Xinjiang Medical University,Urumqi 830011,Xinjiang,China;Department of Dermatology and Venereology,People’s Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830001,Xinjiang,China)

机构地区：[1]新疆医科大学,新疆乌鲁木齐830011 [2]新疆维吾尔自治区人民医院皮肤性病科新疆皮肤病研究重点实验室(XJYS1707)

出　　处：《中国美容医学》2022年第10期191-194,共4页Chinese Journal of Aesthetic Medicine

基　　金：新疆维吾尔自治区自然科学基金资助项目(编号:2019D01C134);“天山创新团队计划”任务书(编号:2020D14006);新疆维吾尔自治区自然科学基金资助项目(编号:2021D01C147)。

摘　　要：瘢痕疙瘩是一种良性纤维增生性皮肤肿瘤,皮损往往超出原始伤口的边界。目前对于瘢痕疙瘩的预防和治疗,主要是手术切除联合局部放疗、类固醇注射及压迫治疗,但这些方法大多疗效有限,因而仍需进一步探索治疗方案。病灶内药物注射疗法经济方便且易被患者广泛接受,然而单一药物注射效果欠佳且容易复发。越来越多的研究发现联合注射疗法总体优于单一注射疗法,如传统类固醇联合其他药物或改进药物注射方式。本文就近几年药物联合注射治疗瘢痕疙瘩的最新研究进展进行综述。Keloid is a benign fibroproliferative skin tumor,the skin lesions often extend beyond the boundary of the original wound.At present,the prevention and treatment of keloids are mainly surgical resection combined with local radiotherapy,steroid injection,and compression therapy,but most of these methods have limited efficacy,so further treatment options are still needed.Intralesional drug injection therapy is economical,convenient and easy to be widely accepted by patients.However,single drug injection has poor effect and is prone to relapse.More and more studies have found that combined injection therapy is generally better than single injection therapy.Such as injecting traditional steroids combined with other drugs or improving drug injection methods.This article briefly reviews the latest research progress of combined drug injection in the treatment of keloids in recent years.

关 键 词：瘢痕疙瘩 注射 联合治疗 复发 进展 

分 类 号：R619.6[医药卫生—外科学]