基于3.0T MRI T2-mapping研究富血小板血浆技术在膝关节骨性关节炎软骨损伤中的应用价值  

Application value of PRP technique in cartilage injury of knee osteoarthritis based on 3.0T MRI T2-mapping

作　　者：熊伟[1] 何希 邓秋云[1] XIONG Wei;HE Xi;DENG Qiuyun(Nanchang Hongdu Hospital of Traditional Chinese Medicine,Nanchang 330000,China)

机构地区：[1]南昌市洪都中医院,江西南昌330000

出　　处：《临床医药实践》2022年第11期803-806,共4页Proceeding of Clinical Medicine

基　　金：江西省卫生健康委员会科技计划项目(项目编号:202211664)。

摘　　要：目的:探讨基于3.0T MRI T2-mapping研究富血小板血浆(PRP)技术在膝关节骨性关节炎(KOA)软骨损伤中的应用价值。方法:选择2020年11月—2021年10月收治的KOA软骨损伤患者62例,按照随机数字表法分为观察组和对照组,每组31例。观察组采取关节腔内PRP注射治疗,对照组无特殊干预。比较两组患者干预前、干预3个月后各个软骨区域T2值及Lysholm膝关节功能评分、Lequesne膝骨性关节炎功能指数(ISOA)评分。结果:观察组干预后各个软骨区域的T2值低于对照组,差异有统计学意义(P<0.05);观察组干预后Lysholm评分高于对照组,ISOA评分低于对照组,差异有统计学意义(P<0.05)。结论:PRP技术治疗KOA软骨损伤能有效改善患者膝关节功能,3.0T MRI T2-mapping有助于评价其临床效果。Objective:To investigate the application value of platelet-rich plasma(PRP)technique in knee osteoarthritis(KOA)cartilage injury based on 3.0T MRI T2-mapping.Methods:A total of 62 patients with KOA cartilage injury who were treated in hospital from November 2020 to October 2021 were selected and divided into a study group and a control group according to the random number table method,with 31 cases in each.The study group received intra-articular PRP injection,while the control group received routine daily life.The T2 value of each cartilage area,Lysholm knee joint function score and Lequesne knee osteoarthritis function index(ISOA)score were compared between the two groups before intervention and after 3 months of intervention.Results:After the intervention,the T2 value of each cartilage area in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:PRP technology can effectively improve the knee joint function of patients with KOA cartilage injury,and 3.0T MRI T2-mapping is helpful to evaluate its clinical effect.

关 键 词：磁共振成像 T2-mapping 富血小板血浆 膝关节骨性关节炎 软骨损伤 

分 类 号：R445.2[医药卫生—影像医学与核医学]