眼科用药研究现状与热点文献计量分析  

Bibliometric analysis of research status and hotspot frontier in ophthalmic drug

作　　者：郭姗姗 姜睿琦 李草 赵志刚[1] GUO Shan-shan;JIANG Rui-qi;LI Cao;ZHAO Zhi-gang(Department of Pharmacy,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院药学部,北京100070

出　　处：《临床药物治疗杂志》2022年第9期18-23,共6页Clinical Medication Journal

摘　　要：目的 揭示国内外眼科用药的研究现状与热点,为开展眼科用药研究提供参考依据。方法 在中国知网期刊全文数据库和Web of Science核心合集数据库中,分别检索1992—2021年已发表的眼科用药相关文献,采用文献计量学方法进行统计和分析。结果 近30年间国外眼科用药研究呈指数增长,且年发文量远大于国内。美国在眼科用药领域优势明显,发文量最多。《国际眼科杂志》收录的中文文献数量最多,美国眼科学会的官方期刊Ophthalmology收录的英文文献数量最多,影响因子也最高。陈祖基发表的中文文献数量最多,URTTI发表的英文文献数量最多。眼科用药的主要研究热点为青光眼、干眼症和抗血管内皮生长因子(VEGF)药物。国外超说明书使用贝伐珠单抗治疗眼部疾病的研究较多,但我国没有相关研究。结论 国内外眼科用药研究需要加强交流合作,建议国内学者加强抗VEGF药物治疗新生血管性眼病的研究。Objective To reveal the national and international research status and hotspot of ophthalmic drug,and to provide references for conducting ocular drug delivery research. Methods The literatures related to ophthalmic medication were collected by searching the China Academic Journals full-text database(CNKI)and the Web of Science Core Collection database e from 1992 to 2021. Statistics and analysis were performed by bibliometric methods. Results The number of English literatures of ocular drug delivery research showed an exponential increase in the past 30 years,which was much higher than that of Chinese. The United States was the most productive country in terms of literatures on ophthalmic medication,with the leading position. International Eye Science has the largest number of Chinese manuscripts,and Ophthalmology—the official journal of the American Academy of Ophthalmology,was the most productive English journal with the highest impact factor.Prof. CHEN Zu-ji and Prof. Urtti were the most productive authors in China and abroad,respectively. Glaucoma,dry eye,and anti-vascular endothelial growth factor(VEGF)drug were the latest high-frequency keywords,indicating the emerging frontiers of ophthalmic medication. There are many studies on the treatment of bevacizumab extensively off-label use in foreign countries,however there is no relevant study in China. Conclusion Researchers collaborations of ophthalmic drug at home and abroad needed to be strengthened,while the domestic scientists need to explore the effectiveness of anti-VEGF therapy in neovascular eye diseases.

关 键 词：眼科用药 文献计量学 研究热点 CITESPACE 

分 类 号：R988.1[医药卫生—药品]