广西壮药血党抗炎镇痛活性研究  

Study on Anti-inflammatory and Analgesic Activity of Guangxi Zhuang Medicine Ardisiae brevicaulis herba

作　　者：陈晓军 华全东 农云开 严克俭 CHEN Xiaojun;HUA Quandong;NONG Yunkai;YAN Kejian(Guangxi Zhuang Autonomous Region Institute of Traditional Medical and Pharmaceutical Sciences,Nanning,Guangxi,530022,China;Guangxi Zhuang Autonomous Region Key Laboratory of Tradition Chinese Medicine Quality Standards,Nanning,Guangxi,530022,China)

机构地区：[1]广西壮族自治区中医药研究院,广西南宁530022 [2]广西壮族自治区中药质量标准研究重点实验室,广西南宁530022

出　　处：《广西科学院学报》2022年第3期276-280,共5页Journal of Guangxi Academy of Sciences

基　　金：广西中药质量标准研究重点实验室学科重点攻关课题(桂中重自201405);广西科技基地和人才专项(桂科AD16380013);广西中医药重点学科建设项目(GZXK-Z-20-75)资助。

摘　　要：为探究广西壮药血党(Ardisiae brevicaulis herba)的抗炎镇痛活性,本文采用二甲苯致小鼠耳廓炎症肿胀实验、小鼠棉球炎性肉芽肿实验、热板法致小鼠疼痛实验、醋酸致小鼠疼痛扭体反应实验进行研究。结果显示,壮药血党能明显降低二甲苯致小鼠耳廓炎症肿胀度,降低小鼠棉球炎性肉芽肿质量,提高小鼠热板痛阈值,减少醋酸致小鼠疼痛扭体反应次数,表明壮药血党具有明显的抗炎镇痛活性。In order to explore the anti-inflammatory and analgesic activity of Guangxi Zhuang medicine Ardisiae brevicaulis herba, xylene-induced mouse auricle inflammatory swelling experiment, mouse cotton ball inflammatory granuloma experiment, hot plate method-induced mouse pain experiment and acetic acid-induced mouse pain writhing reaction experiment were used to study.The results showed that Zhuang medicine A.brevicaulis herba could significantly reduce the auricle inflammation swelling degree induced by xylene, reduce the weight of cotton ball inflammatory granuloma, increase the pain threshold of mice induced by hot plate method and reduce the number of writhing reaction induced by acetic acid.It indicates that Zhuang medicine A.brevicaulis herba has significant activity of anti-inflammatory and analgesic.

关 键 词：广西壮药 血党 抗炎 镇痛 小鼠 

分 类 号：R285.5[医药卫生—中药学]