机构地区:[1]北京中医药大学东方医院风湿科,北京100078 [2]北京中医药大学东方医院儿科,北京100078
出 处:《世界中西医结合杂志》2022年第9期1843-1848,共6页World Journal of Integrated Traditional and Western Medicine
基 金:北京中医药大学自主课题青年教师项目(2017-JYBJS-105)。
摘 要:目的分析原发性干燥综合征(Primary Sjögren′s Syndrome,pSS)患者舌象与涎腺超声改变间的相关性。方法选取2018年9月—2019年8月期间在北京中医药大学东方医院风湿科门诊或病房诊治的102例pSS患者为研究对象。所有研究对象均接受涎腺超声检查,依据评分标准进行超声下涎腺病变总评分并记录病变类型,同时观察并采集舌象信息[包括舌色(淡红舌、淡白舌、红舌、暗紫舌、绛紫舌)、舌形(正常、胖大/齿痕舌、瘦小舌、裂纹舌)、苔色(白苔、黄苔、白黄相间苔、灰黑苔)、苔质(薄苔、厚腻苔、燥苔、少苔、无苔)],并对所收集的相关数据进行统计分析。结果在舌色方面,102例pSS患者中淡红舌10例(9.80%)、淡白舌16例(15.69%)、红舌34例(33.33%)、暗紫舌32例(31.37%)、绛紫舌10例(9.80%)。在舌形方面,102例pSS患者中舌形正常者8例(7.84%)、胖大/齿痕舌33例(32.35%)、瘦小舌20例(19.61%)、裂纹舌41例(40.20%)。在苔色方面,102例pSS患者中无舌苔患者15例,剩余87例pSS患者中白苔22例(25.29%)、黄苔44例(50.57%)、白黄相间苔15例(17.24%)、灰黑苔6例(6.90%)。在苔质方面,102例pSS患者中薄苔8例(7.84%)、厚腻苔39例(38.24%)、燥苔14例(13.73%)、少苔26例(25.49%)、无苔15例(14.71%)。在各组中,暗紫舌组与绛紫舌组、瘦小舌组、黄苔组、少苔组与无苔组pSS患者的涎腺病变总评分最高,差异有统计学意义(P<0.05),其次为红舌组、胖大/齿痕舌组与裂纹舌组、厚腻苔组与燥苔组,差异有统计学意义(P<0.05)。此外,暗紫舌组与绛紫舌组pSS患者的腺体低回声结节比例高于其他舌色组,差异有统计学意义(P<0.05),绛紫舌组pSS患者的腺体萎缩比例高于其他舌色组,差异有统计学意义(P<0.05);胖大/齿痕舌组pSS患者的涎腺低回声结节比例高于其他舌形组,差异有统计学意义(P<0.05),瘦小舌组、裂纹舌组pSS患者的腺体萎缩比例高于其他舌形组,差异�Objective To analyze the correlation between traditional Chinese medicine(TCM)tongue image and salivary gland ultrasound features in patients with primary Sjogren′s syndrome(pSS).Methods A total of 102 patients with pSS who were diagnosed and treated in the outpatient department or ward of the Department of Rheumatology,Dongfang Hospital of Beijing University of Chinese Medicine from September 2018 to August 2019 were included as the research objects..All subjects underwent salivary gland ultrasound examination.According to the scoring standard,the total scores of salivary gland lesions under ultrasound and the types of the lesion were recorded.At the same time,the tongue images of all subjects,including tongue colors(light red,light white,red,dark purple,dark reddish purple),tongue shapes(normal,fat/tooth-marked,thin,and cracked),tongue coating colors(white,yellow,white and yellow,and gray and black),and tongue coating qualities(thin,thick and greasy,dry,less,and no coating),were observed and recorded.Statistical analysis was performed on the collected data.Results In terms of tongue color,10 cases(9.80%)were light red tongue,16 cases(15.69%)were light white tongue,34 cases(33.33%)were red tongue,32 cases(31.37%)were dark purple tongue,and 10 cases(9.80%)were dark reddish purple tongue.In terms of tongue shape,among 102 pSS patients,8 cases(7.84%)had normal tongue shape,33 cases(32.35%)had fat tongue/tooth-marked tongue,20 cases(19.61%)had thin tongue,and 41 cases(40.20%)had cracked tongue.In terms of tongue coating color,15 of 102 pSS patients had no tongue coating,and in the remaining 87 pSS patients,white tongue coating in 22 cases(25.29%),yellow tongue coating in 44 cases(50.57%),white and yellow tongue coating in 15 cases(17.24%),and gray and black tongue coating in 6 cases(6.90%).In terms of the qualities of tongue coating,there were 8 cases(7.84%)of thin tongue coating,39 cases(38.24%)of thick and greasy tongue coating,14 cases(13.73%)of dry tongue coating,26 cases(25.49%)of less tongue coating,and 15 c
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