不同灸量热敏灸治疗膝骨关节炎临床研究  

Clinical Study on Different Amount of Thermal-Sensitive Moxibustion in Treatment of KOA

作　　者：毛珍 江润 段骏 张红星[2] MAO Zhen;JIANG Run;DUAN Jun;ZHANG Hongxing(Wuhan Caidian District People s Hospital,Wuhan 430100,China;Wuhan Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430000,China)

机构地区：[1]武汉市蔡甸区人民医院,湖北武汉430100 [2]武汉市中西医结合医院,湖北武汉430000

出　　处：《针灸临床杂志》2022年第10期52-56,共5页Journal of Clinical Acupuncture and Moxibustion

基　　金：国家自然科学基金重大项目,编号:81590955;武汉市卫生计生委科研计划,编号:WZ20Q12。

摘　　要：目的:观察不同灸量热敏灸治疗膝骨关节炎的临床疗效。方法:将90例患者随机分为3组,分别给予10 min热敏灸(A组)、20 min热敏灸(B组)和30 min热敏灸(C组)。观察治疗前后3组WOMAC各项目评分、Lysholm膝关节功能评分、血清ADAMTS-4及MMPs-3含量变化;观察不同中医证型治疗前后中医证候得分情况。结果:3组治疗前,WOMAC各项目评分、Lysholm膝关节功能评分、血清ADAMTS-4及MMPs-3含量比较,差异无统计学意义(P>0.05);治疗2周后,3组,WOMAC各项目评分及血清ADAMTS-4、MMPs-3含量均降低,Lysholm膝关节功能评分升高,组间比较,差异有统计学意义(P<0.05),其中B组改善程度最大;A组总有效率为73.33%(22/30),B组总有效率为96.67%(29/30),C组总有效率为80%(24/30),组间比较,差异有统计学意义(P<0.05);治疗前,不同证型中医证候积分比较,差异无统计学意义(P>0.05);治疗后,不同证型中医证候积分均明显下降,其中阳虚寒凝型积分差值变化最大。结论:热敏灸能明显改善膝骨关节炎患者关节疼痛、活动度等症状,其中20 min热敏灸疗效最佳,且阳虚寒凝型患者效果更佳。Objective:To observe the clinical effect of different amount of thermal-sensitive moxibustion in treatment of knee osteoarthritis(KOA).Methods:90 patients with KOA were randomly divided into 3 groups,which were treated with thermal-sensitive moxibustion for 10 min(group A),20 min(group B)and 30 min(group C),respectively.The scores of WOMAC and Lysholm knee function,the serum contents of ADAMTS-4 and MMPs-3 were observed before and after the treatment in the three groups.The scores of different TCM syndromes were also observed before and after the treatment in the three groups.Results:There were no statistical differences in the scores of WOMAC and Lysholm knee function,the serum contents of ADAMTS-4 and MMPs-3 among the three groups before the treatment(P>0.05).After 2 weeks of treatment,WOMAC score and the serum contents of ADAMTS-4 and MMPs-3 were decreased,whereas Lysholm knee function score was increased in the three groups,with statistically significant differences among the three groups(P<0.05),and group B showed the greatest improvement.In terms of the total effective rate,it was 73.33%(22/30)in group A,96.67%(29/30)in group B and 80%(24/30)in group C;of which there was statistical difference among the three groups(P<0.05).There was no statistical difference in TCM syndrome scores among the three groups before the treatment(P>0.05);which were significantly decreased in the three groups after the treatment,among which the difference of the integral of Yang deficiency and cold congealing syndrome was most significant.Conclusion:Thermal-sensitive moxibustion can significantly improve joint pain,range of motion and other symptoms in patients with KOA,among which 20 min thermal-sensitive moxibustion has the best effect,and the effect is better in patients with Yang deficiency and cold congealing syndrome.

关 键 词：热敏灸 膝骨关节炎 灸量 

分 类 号：R246.2[医药卫生—针灸推拿学]