机构地区:[1]中国医科大学附属盛京医院放射科,辽宁省沈阳市110004
出 处:《中国组织工程研究》2023年第27期4421-4428,共8页Chinese Journal of Tissue Engineering Research
基 金:辽宁省自然科学基金指导计划(2019-ZD-0794),项目负责人:潘诗农。
摘 要:背景:股骨头骨骺滑脱是影响儿童和青少年常见的髋关节疾病,造成髋关节疼痛及跛行。股骨头骨骺滑脱的发病率差异很大,病因与性别、机械、内分泌、肥胖和遗传等因素相关。目的:综述股骨头骨骺滑脱的核心机制,讨论基于病理生理机制的影像学表现及定量指标评价、治疗方法进展及尚未解决的问题。方法:第一作者以“Slipped epiphysis of femoral head,Complications,AVN,FAI,hip chondrolysis,SCFE imaging diagnose,X-ray,CT,MRI”为英文数据库检索词,以“股骨头骨骺滑脱、并发症、AVN、FAI、软骨溶解、X射线、CT、MRI”为中文数据库检索词,通过计算机检索PubMed、Web of Science、Embase、中国知网及万方数据库中的相关文献,并进行筛选、评估、归纳,最终纳入63篇相关文献进行综述。结果与结论:(1)目前关于股骨头骨骺滑脱发病机制的国际主流观点倾向于机械损伤因素、内分泌因素及肥胖遗传多种因素的共同作用。(2)影像手段在股骨头骨骺滑脱诊断中可发挥重要作用,X射线片及三维CT在股骨头骨骺滑脱诊断中较为常用,MRI可用来观察除骨质改变以外的骺板水肿等变化。(3)不同的诊断方式及测量参数能够全面且定量地从骨质改变、软化损伤及肌肉萎缩等方面来评估股骨头骨骺滑脱患者的情况。(4)股骨头骨骺滑脱的并发症包括股骨头缺血坏死、股骨髋臼撞击征、软骨溶解和退行性关节炎,会造成长期且具有破坏性的临床预后。(5)基于主要病理机制,治疗手段主要包括手术、内分泌及康复治疗,且取得了一定的成果。(6)临床上,股骨头骨骺滑脱患者多因患侧髋部及膝部疼痛及跛行就诊,影像学表现以骺板增宽、股骨头骨骺及干骺端相对移位为主。(7)因此,针对股骨头骨骺滑脱患者临床病理特征及并发症的特点,医生需正确认识影像学检查在股骨头骨骺滑脱中的辅助诊断作用,需要做好�BACKGROUND: Slipped capital femoral epiphysis is a common hip disease affecting children and adolescents, causing hip pain and lameness. The incidence of slipped capital femoral epiphysis varies widely, and the etiology is related to gender, mechanical, endocrine, obesity, and genetic factors.OBJECTIVE: To review the core mechanism of slipped capital femoral epiphysis, to discuss the imaging manifestations and quantitative index evaluation based on the pathophysiological mechanism, the progress of treatment methods and unresolved problems.METHODS: The first author used “slipped epiphysis of femoral head, complications, AVN, FAI, hip chondrolysis, SCFE imaging diagnose, X-ray, CT, MRI” as English search terms, and “slipped epiphysis of femoral head, complications, AVN, FAI, chondrolysis, X-ray, CT, MRI” as Chinese search terms. Relevant articles published in PubMed, Web of Science, Embase, CNKI, and Wanfang databases were searched by computer, and screened and evaluated, summed up, and finally 63 related articles were included for review. RESULTS AND CONCLUSION:(1) The current international mainstream views on the pathogenesis of slipped capital femoral epiphysis tend to be the combined effects of mechanical injury factors, endocrine factors and obesity genetic factors.(2) Imaging methods play an increasingly important role in the diagnosis of slipped capital femoral epiphysis. X-ray and three-dimensional CT are more commonly used in the diagnosis of slipped capital femoral epiphysis. MRI can be used to observe changes in epiphyseal plate edema other than bone changes.(3) Different diagnostic methods and measurement parameters can comprehensively and quantitatively evaluate the condition of slipped capital femoral epiphysis patients from the aspects of bone changes, softening injuries and muscle atrophy.(4) Complications of slipped capital femoral epiphysis include avascular necrosis of the femoral head, femoroacetabular impingement sign, chondrolysis, and degenerative arthritis, resulting in long-term and
关 键 词:股骨头骨骺滑脱 股骨头骨骺滑脱并发症 股骨头缺血性坏死 股骨髋臼撞击症 髋关节软骨溶解 X射线 CT MRI
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