机构地区:[1]新疆医科大学第一附属医院心力衰竭科,新疆乌鲁木齐830000
出 处:《中国医药导报》2022年第30期70-74,共5页China Medical Herald
基 金:新疆维吾尔自治区自然科学基金重点资助项目(2021D01D17)。
摘 要:目的调查新疆地区三级甲等(三甲)医院住院慢性心力衰竭(CHF)患者的人口学资料。临床特征及管理。方法本研究为横断面研究。入选2018年1月至2020年9月,新疆地区省级三甲医院(新疆医科大学第一附属医院、新疆维吾尔自治区人民医院、新疆维吾尔自治区中医医院)及3所市级三甲医院(喀什地区第二人民医院、伊犁州人民医院、昌吉州中医医院)连续住院治疗的1500例CHF患者。收集入选患者一般信息、危险因素、CHF病因、检查结果、用药情况等临床资料。结果最终纳入1451例CHF患者,其中男967例;年龄(64.14±13.13)岁;中位住院天数9 d。射血分数下降型CHF(HFrEF)和心功能Ⅲ级患者占比最高。HFrEF患者ACEI/ARB/ARNI,β受体阻滞剂及醛固酮受体拮抗剂用药率分别为87.2%、89.5%和88.0%。省级住院CHF患者年龄、男性占比高于市级三甲医院,住院天数短于市级三甲医院,差异有统计学意义(P<0.05)。省级住院CHF患者NT-Pro BNP/BNP检查率,HFrEF及心功能Ⅳ级者,行起搏介入、冠状动脉介入或搭桥者及合并高尿酸血症、贫血、肾功能不全者占比高于市级三甲医院(P<0.05)。省级HFrEF患者使用ARNI及伊伐布雷定者比例高于市级三甲医院;使用醛固酮受体拮抗剂患者比例低于市级三甲医院(P<0.05)。结论新疆地区三甲医院住院CHF病因以冠心病为主。省级三甲医院住院的CHF患者年龄更大,心功能更差。省级与市级三甲医院住院的HFrEF患者指南推荐的标准化药物使用比例无显著差异。Objective To investigate the demographic data,clinical characteristics,and management of inpatients with chronic heart failure(CHF)in a tertiary hospital in Xinjiang.Methods This study was a cross-sectional study.From January 2018 to September 2020,1500 patients with CHF who were continuously hospitalized in the provincial tertiary hospitals in Xinjiang(the First Affiliated Hospital of Xinjiang Medical University,the People’s Hospital of Xinjiang Uygur Autonomous Region,and the Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region)and three municipal tertiary hospitals(the Second People’s Hospital of Kashgar,Yili Prefecture People’s Hospital,Changji Prefecture Traditional Chinese Medicine Hospital)were selected.The general information,risk factors,etiology of CHF,examination results,drug use,and other clinical data of the selected patients were collected.Results A total of 1451 CHF patients were finally included,including 967 males;the age was(64.14±13.13)years;the median hospital stay was nine days.Patients with CHF with reduced ejection fraction(HFrEF)and classⅢcardiac function accounted for the highest proportions.The rates of ACEI/ARB/ARNI,β-blocker,and aldosterone receptor antagonist use in HFrEF patients were 87.2%,89.5%,and 88.0%,respectively.The proportion of CHF patients hospitalized in provincial tertiary hospitals was higher than that of municipal tertiary hospitals,while the length of stay was shorter than that of century tertiary hospitals,and the differences were statistically significant(P<0.05).The rate of NT-Pro BNP/BNP examination in CHF patients in provincial tertiary hospitals,patients with HFrEF and cardiac function gradeⅣ,patients undergoing pacing intervention,coronary intervention or bypass,and the proportion of hyperuricemia,anemia,and renal insufficiency in provincial tertiary hospitals were higher in the municipal tertiary hospital(P<0.05).The proportion of HFrEF patients in provincial tertiary hospitals were higher than that of municipal tertiary hospita
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