从虚、毒、痰、瘀辨治特发性肺纤维化  

Differentiation and treatment on idiopathic pulmonary fibrosis from deficiency, toxin, phlegm and stasis

作　　者：于睿智 庞立健[2] 王天娇 吕晓东[1] YU Rui-zhi;PANG Li-jian;WANG Tian-jiao;LYU Xiao-dong(Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China;The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China)

机构地区：[1]辽宁中医药大学,沈阳110032 [2]辽宁中医药大学附属医院,沈阳110032

出　　处：《中华中医药杂志》2022年第10期5815-5818,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：辽宁省“兴辽英才计划”项目高水平创新团队(No.XLYC1808011);辽宁省科学技术计划项目(No.2019JH210300023);沈阳市中青年科技人才支持计划项目(No.RC200156)。

摘　　要：特发性肺纤维化是肺系难治性疾病,现阶段对于特发性肺纤维化的中医辨治多从所属中医疾病入手,尤以肺痿居多,笔者结合古今文献和临床案例,认为特发性肺纤维化的病机可从病理因素角度出发,概括为肺虚、邪毒、血瘀、痰结。在临床治疗中,运用异病同治理论,可从虚、毒、痰、瘀对其进行辨治,减少病名对疾病治疗的禁锢,为特发性肺纤维化临床辨治提供新思路,并指出特发性肺纤维化的发病总属本虚标实之证,其发病病机源于久病而正气亏虚,致痰、瘀、毒互结,在治疗中应辨明虚、毒、痰、瘀所现之症,并做到动态审查,以常达变,扶正兼祛邪。Idiopathic pulmonary fibrosis is a refractory disease of the lung system. At this stage, the TCM syndrome differentiation and treatment of idiopathic pulmonary fibrosis mostly starts with its TCM diseases, especially pulmonary flaccidity.Combined with ancient and modern literature and clinical cases, the author believes that the pathogenesis of idiopathic pulmonary fibrosis can be summarized as lung deficiency, evil toxin, blood stasis and phlegm knot from the perspective of pathological factors. Using the theory of treating different diseases with same method in clinical treatment, it can be differentiated and treated from ‘deficiency’, ‘toxicity’, ‘phlegm’ and ‘stasis’, so as to reduce the confinement of disease names on disease treatment.It provides new ideas for the clinical differentiation and treatment of idiopathic pulmonary fibrosis, and points out that the pathogenesis of idiopathic pulmonary fibrosis is primary asthenia-secondary sthenia syndrome. The pathogenesis of the disease stems from chronic illness and deficiency of righteousness, resulting in phlegm, blood stasis, and toxins. In the treatment, the symptoms of ‘deficiency’, ‘toxicity’, ‘phlegm’ and ‘blood stasis’ should be identified, and a dynamic review should be carried out,so as to achieve change, strengthen the body and eliminate pathogenic factors.

关 键 词：特发性肺纤维化 虚、毒、痰、瘀 发病原理 辨治思路 异病同治 中医 

分 类 号：R259[医药卫生—中西医结合] R249[医药卫生—中医内科学]