十堰市婴幼儿维生素D水平现状及相关因素分析  

Analysis of the Status Quo of Vitamin D Levels in Infants and Young Children and Related Factors

作　　者：刘芳[1] 王爽[1] 曾晴雯 梅文龙[1] 纪宏先 李珍[1] LIU Fang;WANG Shuang;ZENG Qingwen;MEI Wenlong;JI Hongxian;LI Zhen(Shiyan Materal and Child Health Hospital,Shiyan,Hubei,442000,China)

机构地区：[1]十堰市妇幼保健院,湖北十堰442000

出　　处：《中国社会医学杂志》2022年第5期561-565,共5页Chinese Journal of Social Medicine

基　　金：十堰市科技局引导性科研项目(21Y95)。

摘　　要：目的 了解十堰市婴幼儿维生素D水平现状,并分析其相关因素,为今后开展儿童保健宣教提供依据。方法 选取2020年10月—2021年6月,在十堰市妇幼保健院及县级(包括竹山县及郧西县)妇幼保健院进行健康体检的婴幼儿(0~6岁)749名为研究对象,运用荧光免疫检测技术测量血清中25-羟基维生素D(25-OH-VitD)的水平,同时由监护人填写调查问卷,将研究结果用SPSS 26.0软件进行统计学分析。结果 749名婴幼儿25-OH-VitD水平为(36.27±9.09)ng/mL,维生素D缺乏、不足比率分别为22.16%、19.36%。不同性别、不同年龄及不同父亲文化程度间的婴幼儿维生素D水平分组间差异均无统计学意义(均P>0.05)。但不同居住地、6月龄内喂养情况、孕期妈妈是否口服维生素D、不同母亲文化程度、每日户外日照时间及婴幼儿是否额外摄入维生素D补充剂间的婴幼儿维生素D水平分组间差异具有统计学意义(均P<0.05)。多因素Logistic回归分析提示,农村、纯母乳喂养、户外日照时间<2 h及未补充维生素D是婴幼儿维生素D缺乏的危险因素。结论 十堰市婴幼儿维生素D水平现状存在城乡差距,应加强宣教婴幼儿维生素D补充的重要性,合理安排婴幼儿的户外日照时间,特别是农村及纯母乳喂养的婴幼儿。Objective To understand the current status of vitamin D levels in infants and young children in Shiyan city, to analyze its related factors, and to provide a basis for future child health education.Methods A total of 749 infants(0-6 years old)who underwent physical examinations at Shiyan Maternal and Child Health Hospital and county-level(including Zhushan county and Yunxi county)Maternity and Child Health Hospital from October 2020 to June 2021 were selected as the research subjects.Fluorescence immunoassay technology was used to measure the level of 25-hydroxyvitamin D(25-OH-VitD)in the serum.At the same time, the guardian filled out the survey questionnaire, and the results were statistically analyzed with SPSS 26.0 software.Results The 25-OH-VitD level of 749 infants and young children was 36.27±9.09 ng/mL,and the rates of vitamin D deficiency and deficiency were 22.16% and 19.36%,respectively.There were no statistically significant differences in the vitamin D levels of infants and young children between different genders, different ages and different fathers’ education levels(all P>0.05).However, there were differences in the vitamin D levels of infants and young children between different places of residence, feeding conditions within 6 months, whether mothers took vitamin D during pregnancy, different mothers’ educational level, daily outdoor sunshine time, and whether infants and young children took extra vitamin D supplements.And the differences were statistically significance(all P<0.05).Multivariate logistic regression analysis suggested that rural areas, exclusive breastfeeding, outdoor sunshine time less than 2 h and no vitamin D supplementation were risk factors for vitamin D deficiency in infants and young children.Conclusion There is an urban-rural gap in the vitamin D level of infants and young children in Shiyan city.It is necessary to strengthen education on the importance of vitamin D supplementation for infants and young children, and arrange the outdoor sunshine time for infants and yo

关 键 词：婴幼儿 维生素D 相关因素 

分 类 号：R591.44[医药卫生—内科学] R174[医药卫生—临床医学]