儿童生长发育评估常用检测指标及其检测方法学研究进展  

Research advances on common detection biomarkers and methodology of children′s growth and development assessment

作　　者：李菁[1] 谢小兵[1] Li Jing;Xie Xiaobing(Department of Medical Laboratory and Pathology Center,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China)

机构地区：[1]湖南中医药大学第一附属医院医学检验与病理中心,长沙410007

出　　处：《中华预防医学杂志》2022年第9期1211-1217,共7页Chinese Journal of Preventive Medicine

基　　金：湖南中医药大学一级学科开放基金项目(2018YXJS02)。

摘　　要：随着现代社会信息高速传播, 我国居民越来越注重科学化的育儿理念, 使得儿童预防保健行业得到了快速发展。儿童生长发育规律极其复杂, 需要根据不同的生长发育评估角度, 检测不同的指标。人生长激素(hGH)、胰岛素样生长因子-1(IGF-1)、胰岛素样生长因子结合蛋白-3(IGFBP-3)、甲状腺激素(thyroid hormone)、性激素(sex hormone)、抗苗勒管激素(AMH)及25-羟基维生素D(25-OH VD)等是监测儿童生长发育情况的常用指标。本文旨在阐释生长发育常用指标的概念与特点, 概述近年来研发的生长发育评估常用指标的检测方法, 为儿童预防保健选择合适的检测指标提供参考。With the rapid dissemination of information in modern society,Chinese residents pay more attention to the scientific concept of childcare,which makes the child prevention and health care industry develop rapidly.The law of children′s growth and development is extremely complex,so it is necessary to detect different biomarkers according to different growth and development evaluation angles.Human growth hormone(hGH),insulin-like growth factor-1(IGF-1),insulin-like growth factor binding protein-3(IGFBP-3),thyroid hormone,sex hormone,anti-müllerian hormone(AMH)and 25-hydroxy vitamin D(25-OH VD)are common biomarkers to monitor children′s growth and development.This article aims to explain the concept and characteristics of common biomarkers of growth and development,summarize the detection methods of common biomarkers of growth and development evaluation developed in recent years,and provide a reference for children′s prevention and health care to select appropriate detection biomarkers.

关 键 词：儿童 激素 化学发光测定法 生长发育 预防保健 

分 类 号：R179[医药卫生—妇幼卫生保健]