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作 者:顾莉[1] GU Li(Department of Otaryngology,Guanyun County People's Hospital,Lianyungang,Jiangsu Province,222200 China)
机构地区:[1]连云港市灌云县人民医院五官科,江苏连云港222200
出 处:《系统医学》2022年第17期65-68,72,共5页Systems Medicine
摘 要:目的分析鼻内镜下手术对复发性Ⅲ型慢性鼻-鼻窦炎鼻息肉的治疗效果。方法纳入连云港市灌云县人民医院2018年1月-2021年10月122例复发性Ⅲ型慢性鼻-鼻窦炎鼻息肉患者为研究对象,经随机数表法分组,每组61例。对照组采用传统根治术,观察组患者采用鼻内镜手术。对比两组临床疗效、手术前后炎症因子和并发症。结果观察组总有效率为98.36%,明显高于对照组的78.69%,差异有统计学意义(P<0.05)。观察组并发症发生率为3.28%,低于对照组的16.39%,差异有统计学意义(χ^(2)=5.915,P<0.05);观察组治疗后肿瘤坏死因子-α、白细胞介素-4和白细胞介素-6水平分别为(34.12±7.32)ng/L、(30.27±4.96)ng/L和(27.68±3.56)ng/L,低于对照组的(47.21±8.64)ng/L、(38.42±5.21)ng/L和(35.24±3.18)ng/L,差异有统计学意义(P<0.05)。结论予以复发性Ⅲ型慢性鼻-鼻窦炎鼻息肉患者鼻内镜下手术,效果好,可减少炎症因子释放,术后并发症少,有广泛应用价值。Objective To analyze the therapeutic effect of nasal endoscopic surgery on recurrent typeⅢchronic rhinosinusitis and nasal polyps.Methods A total of 122 patients with recurrent type III chronic rhinosinusitis and nasal polyps from January 2018 to October 2021 in Guanyun County People's Hospital of Lianyungang City were included as the research objects,and were divided into groups by random number table,with 61 cases in each group.The control group was treated with traditional radical surgery,while the observation group was treated with endoscopic nasal surgery.The clinical efficacy,inflammatory factors and complications before and after surgery were compared between the two groups.Results The total effective rate of the observation group was 98.36%,which was significantly higher than that of the control group,which was 78.69%,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was 3.28%,which was lower than 16.39%in the control group,and the difference was statistically significant(χ^(2)=5.915,P<0.05).The interleukin-6 levels were(34.12±7.32)ng/L,(30.27±4.96)ng/L and(27.68±3.56)ng/L,respectively,which were lower than those of the control group(47.21±8.64)ng/L,(38.42±5.21)ng/L and(35.24±3.18)ng/L,the difference was statistically significant(P<0.05).Conclusion Nasal endoscopic surgery for patients with recurrent typeⅢchronic rhinosinusitis and nasal polyps has a good effect,can reduce the release of inflammatory factors,and has fewer postoperative complications,which has a wide application value.
关 键 词:鼻内镜手术 复发性Ⅲ型慢性鼻-鼻窦炎鼻息肉 临床疗效 炎症因子 并发症
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