正常国人青年人群三对半规管视频头脉冲及头脉冲抑制试验的增益特征  

Gain characteristics of three pairs of semicircular canals in video head impulse paradigm test and suppression head impulse paradigm test in healthy young Chinese population

作　　者：张青 张勤[1] 吴琼[1] 金玉莲 陈向平 沈敏 陈建勇[1] 杨军[1] ZHANG Qing;ZHANG Qin;WU Qiong;JIN Yulian;CHEN Xiangping;SHEN Min;CHEN Jianyong;YANG Jun(Department of Otorhinolaryngology-Head&Neck Surgery,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai Jiaotong University School of Medicine Ear Institute,Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases,Shanghai,200092,China)

机构地区：[1]上海交通大学医学院附属新华医院耳鼻咽喉-头颈外科上海交通大学医学院耳科学研究所上海耳鼻疾病转化医学重点实验室,上海200092

出　　处：《临床耳鼻咽喉头颈外科杂志》2022年第9期659-664,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金资助项目(No:81970891,82171137);上海市科技创新行动计划(No:21S31900600)。

摘　　要：目的:总结正常青年人群三对半规管头脉冲试验(HIMP)及头脉冲抑制试验(SHIMP)的增益特征。方法:使用视频头脉冲测试仪EyeSeeCam对纳入研究的40例正常青年志愿者进行三对半规管的HIMP和SHIMP检测,分别记录两种检查扫视波的引出率及增益值,并对增益值进行比较分析。结果:40例正常青年人三对半规管HIMP测试水平半规管60 ms瞬时增益值左、右侧分别为1.11±0.07和1.08±0.07,左侧水平半规管60 ms瞬时增益值略高于右侧(P<0.05);水平半规管回归增益值左、右侧分别为1.09±0.06和1.10±0.06,垂直半规管回归增益值为:右前1.08±0.12、左后1.07±0.11、右后1.41±0.16、左前1.42±0.16,三对半规管左、右侧回归增益值比较差异无统计学意义(P>0.05)。SHIMP测试水平半规管60 ms瞬时增益值左右侧分别为1.08±0.08和1.06±0.07;水平半规管回归增益值左右侧分别为1.06±0.07和1.07±0.06,垂直半规管回归增益值为:右前1.06±0.13、左后1.08±0.16、右后1.49±0.16、左前1.39±0.15,SHIMP测试水平半规管60 ms瞬时增益、水平回归增益、右前左后回归增益在左右两侧之间比较均差异无统计学意义(P>0.05),右侧的左前右后回归增益值略高于左侧(P<0.05)。在水平共轭面,HIMP测试60 ms瞬时增益及回归增益值均略大于SHIMP(P<0.05),但在两个垂直共轭面差异无统计学意义(P>0.05)。对同一测试的三个共轭面增益值两两比较结果显示:左前右后共轭面HIMP和SHIMP增益值高于水平及右前左后共轭面(P<0.05),水平共轭面与右前左后共轭面增益值之间差异无统计学意义(P>0.05)。结论:HIMP和SHIMP检测的三对半规管不同共轭面之间增益值略有差异,建议各检测中心分别建立自己实验室的正常参考值,并定期校正。Objective To summarize gain characteristics of three pairs of semicircular canals in head impulse paradigm(HIMP)and suppression head impulse paradigm(SHIMP)in healthy young Chinese population.Methods HIMP and SHIMP tests were performed on 40 healthy young volunteers enrolled as study group,by using EyeseeCam examiantion system(Interacoustics,Denmark).The elicitation rates and gain values of the two saccades were recorded,and the gain values were compared and analyzed.Results The results of 40 healthy young people were as follows:in HIMP,the instantaneous gain at 60 ms of the horizontal semicircular canals were 1.11±0.07 on the left side and 1.08±0.07 on the right side;the regression gain of the horizontal semicircular canals were 1.09±0.06 on the left side and 1.10±0.06 on the right side;the regression gain of the vertical semicircular canals were 1.08±0.12 on the right anterior,1.07±0.11 on the left posterior,1.41±0.16 on the right posterior and 1.42±0.16 on the left anterior.So in HIMP,no significant difference could be found between left and right side in both horizontal and vertical semicircular canal conjugate plane regarding regression gain(P>0.05),except that 60 ms instantaneous gain on the left horizontal semicircular canals was slightly higher than that on the right side(P<0.05).The instantaneous gain values of the horizontal semicircular canal at 60 ms in SHIMP were 1.08±0.08 on the left side and 1.06±0.07 on the right side;the regression gain in horizontal semicircular canals were 1.06±0.07 on the left side and 1.07±0.06 on the right side,respectively;the regression gains of vertical semicircular canal were 1.06±0.13,1.08±0.16,1.49±0.16,1.39±0.15,on the right anterior,left posterior,right posterior,and left anterior side.So in SHIMP,no significant difference could be found in 60 ms instantaneous gain in horizontal conjugate plane,regression gain in horizontal conjugate plane and regression gain in right anterior left posterior conjugate plane(P>0.05),while the regression gain of the lef

关 键 词：头脉冲试验 头脉冲抑制试验 前庭眼反射 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]