变态反应检测与诊断的临床应用及意义  

Clinical use and significance of allergy testing and diagnostics

作　　者：程雷[1,2,3] 许秋艳 陈浩 CHENG Lei;XU Qiuyan;CHEN Hao(Department of Otorhinolaryngology,The First Affiliated Hospital,Nanjing Medical University,Nanjing 210029,Jiangsu,China;Clinical Allergy Center,The First Affiliated Hospital,Nanjing Medical University,Nanjing 210029,Jiangsu,China;International Centre for Allergy Research,Nanjing Medical University,Nanjing 210029,Jiangsu,China;Department of Pediatrics,Suzhou Science&Technology Town Hospital,Nanjing Medical University,Suzhou 215153,Jiangsu,China;Department of Allergy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei,China)

机构地区：[1]南京医科大学第一附属医院/江苏省人民医院耳鼻咽喉科,江苏南京210029 [2]南京医科大学第一附属医院/江苏省人民医院过敏诊疗中心,江苏南京210029 [3]南京医科大学国际变态反应研究中心,江苏南京210029 [4]南京医科大学附属苏州科技城医院儿科,江苏苏州215153 [5]华中科技大学同济医学院附属同济医院过敏反应科,湖北武汉430030

出　　处：《山东大学耳鼻喉眼学报》2022年第3期1-6,共6页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：江苏高校优势学科建设工程(JX10231801)。

摘　　要：变态反应疾病是当今全球最常见的疾病之一,而且疾病负担继续在增加。明确变应原致敏并识别引起变态反应疾病的变应原对于制定疾病管理策略至关重要。介绍目前国内外在诊断IgE介导的Ⅰ型变态反应中最常用的体内和体外检测方法及其临床意义。Allergic diseases are among the most prevalent diseases worldwide and their burden on healthcare systems continues to increase. Confirmation of allergen sensitization and the identification of causal allergens are essential for developing management strategies for these maladies. This paper provides an updated introduction of the most commonly used detection methods, both in vivo and in vitro, in the diagnosis of type I IgE-mediated allergy and its clinical significance.

关 键 词：变应原 免疫球蛋白E 皮肤试验 血清学检测 诊断 

分 类 号：R392.8[医药卫生—免疫学] R765.21[医药卫生—基础医学]