发热伴血小板减少综合征研究热点的可视化分析  

Visual analysis of research hotspots in severe fever with thrombocytopenia syndrome

作　　者：周妍希 武瑞君 林玲 刘元妮 张伟 王玺 陈志海 朱鏐娈 ZHOU Yan-xi;WU Rui-jun;LIN Ling;LIU Yuan-ni;ZHANG Wei;WANG Xi;CHEN Zhi-hai;ZHU Liu-luan(Beijing Institute of Infectious Diseases,Beijing Key Laboratory of Emerging Infectious Diseases,Institute of Infectious Diseases,Beijing Ditan Hospital,Capital Medical University,100015,China)

机构地区：[1]北京市感染性疾病研究中心,首都医科大学附属北京地坛医院传染病研究所新发突发传染病北京市重点实验室,100015 [2]中国生物技术发展中心,北京100039 [3]烟台市奇山医院感染性疾病科,264001 [4]首都医科大学附属北京地坛医院感染性疾病临床中心,100015

出　　处：《传染病信息》2022年第5期426-432,共7页Infectious Disease Information

基　　金：国家自然科学基金(82072295);教育部2020年长江学者项目;2021年国家临床重点专科建设项目。

摘　　要：目的 对发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome, SFTS)的相关文献进行文献计量学和可视化分析,探寻近年来的研究现状、热点及趋势,为临床治疗和基础研究提供参考。方法 以Web of Science(WOS)核心合集和中国知网(China national knowledge infrastructure, CNKI)数据库为文献来源,检索2011年1月1日—2021年12月31日有关SFTS的文献,导入CiteSpace.5.7.R2软件,以国家、作者、文献共被引、关键词为节点进行可视化分析,并绘制相关图谱。结果 在WOS核心合集共检索到797篇文献,在CNKI数据库共检索到714篇文献。相关领域发文量总体呈上升趋势,中国发文量居首位,美国和日本之间机构合作密切。研究热点集中在发病机制、抗体、特异性治疗等领域。非结构蛋白、临床预后、血小板减少、SFTS病毒感染的靶细胞等将是未来的研究重点。结论 国内外关于SFTS的研究逐渐成熟,新型布尼亚病毒、免疫功能、预后是研究重点,但是对SFTS发病机制和病毒受体尚不清楚,仍须进一步探索。Objective To analyze the bibliometrics and visualization of the related literatures of severe fever with thrombocytopenia syndrome, and to explore the current research status, hotspots and research trends in recent years, so as to provide reference for clinical and basic research. Methods Web of Science(WOS) core database and CNKI China National Knowledge Infrastructure database were used as literature sources to search the relevant literatures on severe fever with thrombocytopenia syndrome on January 1, 2011 and December 31, 2021. CiteSpace.5.7.R2 software was imported. The countries, authors, co-cited literatures and keywords were used as nodes for visual analysis, and the relevant maps were drawn. Results A total of 797 articles were retrieved in the WOS core collection and 714 articles in the CNKI database. The number of documents issued in relevant fields is generally on the rise, China ranks first in the number of documents issued, and institutional cooperation between the United States and Japan is close. Research hotspots focus on the pathogenesis, antibodies, specific therapy and other fields. Nonstructural proteins, clinical prognosis, thrombocytopenia, and target cells infected by SFTS will be the focus of future research. Conclusions The research on SFTS at home and abroad has gradually matured, and sftsv, immune function, and prognosis are the research priorities, but the pathogenesis and viral receptors of SFTS are still unclear and still need further exploration.

关 键 词：发热伴血小板减少综合征 血小板减少 布尼亚病毒 淮阳山病毒 大别班达病毒 研究热点 发展趋势 CITESPACE 文献计量学 知识图谱 

分 类 号：R512.99[医药卫生—内科学]