中医药调节肠道菌群治疗哮喘研究概述  

Review on Regulating Intestinal Flora with Traditional Chinese Medicine in the Treatment of Asthma

作　　者：才振国[1] 李竹英[2] 车琳琳[1] CAI Zhenguo;LI Zhuying;CHE Linlin(Heilongjiang University of Traditional Chinese Medicine,Harbin 150006,China;The First Affiliated Hospital,Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150006 [2]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《山东中医杂志》2022年第11期1240-1243,共4页Shandong Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:82074365)。

摘　　要：现代研究显示肺与肠共同由原始消化管的内胚层发育而来,临床研究也表明胃肠道疾病和呼吸系统疾病常伴随发生。在中医藏象理论中,肺与大肠相表里,二者在生理、病理上相互影响。从调节肠道菌群角度探索中医药对哮喘的治疗具有启示意义,其作用机制可能为:(1)肠道菌群变化能够间接影响免疫系统的功能;(2)肠道菌群能够影响药物的代谢;(3)肠道菌群能够合成某些代谢产物影响自身的免疫平衡。参考文献30篇。Modern studies have shown that the lung and intestine both develop from the endoderm of the primary digestive tract,and clinical studies have also shown that gastrointestinal diseases and respiratory diseases occur simultaneously.According to the visceral manifestation theory of traditional Chinese medicine(TCM),lung and large intestine are related interiorly and exteriorly,and would affect each other physiologically and pathologically.From the perspective of regulating the intestinal flora,TCM treating asthma might be through the possible mechanism as follows:(1)Changes in the intestinal flora can indirectly affect the function of the immune system;(2)The intestinal flora can affect the metabolism of drugs;(3)The intestinal flora can synthesize certain metabolites to affect immune balance.There are 30 papers cited in the references.

关 键 词：肠道菌群 哮喘 肺 大肠 藏象 免疫功能 

分 类 号：R256.12[医药卫生—中医内科学]