不同终止妊娠方式对异位妊娠的影响评价研究  

Evaluation of the Effect of Different Methods of Termination of Pregnancy on Ectopic Pregnancy

作　　者：胡发令 HU Faling(Department of Obstetrics and Gynecology,Nanping Second Hospital,Nanping,Fujian Province,354200 China)

机构地区：[1]南平市第二医院妇产科,福建南平354200

出　　处：《中外医疗》2022年第17期82-86,共5页China & Foreign Medical Treatment

摘　　要：目的评价药物保守方法、手术对异位妊娠的治疗效果及给患者造成的影响。方法回顾性分析2019年7月—2021年7月就诊于南平市第二医院妇产科的80例异位妊娠患者的临床资料,以不同终止妊娠方式分为对照组、研究组,各40例。对照组采取药物保守治疗,研究组采取手术治疗。对比两组住院时间、人绒毛膜促性腺激素恢复正常时间、不良反应发生率、再次妊娠情况及治疗前后黄体生成素、促卵泡激素、睾酮水平。结果研究组住院时间、人绒毛膜促性腺激素恢复正常时间分别为(13.16±4.20)d、(9.46±3.58)d,均短于对照组的(19.19±5.53)d、(16.37±4.59)d,差异有统计学意义(t=5.492、7.508,P<0.05)。研究组不良反应发生率(10.00%)低于对照组(20.00%),但差异无统计学意义(χ^(2)=1.569,P>0.05)。研究组宫内妊娠率(95.00%)高于对照组(70.00%),异位妊娠率(5.00%)低于对照组(30.00%),差异有统计学意义(χ^(2)=8.658,P<0.05)。治疗前,研究组黄体生成素、促卵泡激素、睾酮水平分别为(16.24±3.67)IU/L、(5.98±1.32)U/L、(6.98±1.57)nmol/L,与对照组的(16.13±3.33)IU/L、(5.75±1.11)U/L、(6.74±1.46)nmol/L比较,差异无统计学意义(t=0.140、0.843、0.708,P=0.889、0.402、0.481);治疗后,研究组黄体生成素、促卵泡激素、睾酮水平分别为(6.45±0.24)IU/L、(3.04±0.69)U/L、(1.45±0.12)nmol/L,均低于对照组的(8.33±1.35)IU/L、(4.35±0.89)U/L、(3.39±0.78)nmol/L,差异有统计学意义(t=8.672、7.357、15.547,P<0.05)。结论手术对异位妊娠的治疗效果优于药物保守方法,其对患者恢复速度、再次妊娠情况、不良反应发生状况、激素水平均有更加积极的影响。Objective To evaluate the therapeutic effect of conservative drug methods and surgery on ectopic pregnancy and the impact on patients.Methods The clinical data of 80 ectopic pregnancy patients who presented to the obstetrics and gynecology department of Nanping Second Hospital from July 2019 to July 2021 were retrospectively analyzed.Divided into control group and study group according to the different methods of termination of pregnancy,40 patients the control group in each group,received conservative drug treatment,and the study group received surgical treatment.The length of hospital stay,the time to return to normal human chorionic gonadotropin,the incidence of side effects,the situation of re-pregnancy,the levels of luteinizing hormone,follicle-stimulating hormone,and testosterone before and after treatment were compared between two groups.Results The length of hospital stay and the time to return to normal for human chorionic gonadotropin in the study group were(13.16±4.20)d and(9.46±3.58)d,respectively,which were shorter than(19.19±5.53)d and(16.37±4.59)d in the control group,the difference was statistically significant(t=5.492,7.508,P<0.05).The incidence of adverse reactions in the study group(10.00%)was lower than that in the control group(20.00%),but the difference was not statistically significant(χ^(2)=1.569,P>0.05).The intrauterine pregnancy rate(95.00%)of the study group was higher than that of the control group(70.00%),and the ectopic pregnancy rate(5.00%)was lower than that of the control group(30.00%),the difference was statistically significant(χ^(2)=8.658,P<0.05).Before treatment,the levels of luteinizing hormone,folliclestimulating hormone and testosterone in the study group were(16.24±3.67)IU/L,(5.98±1.32)U/L,and(6.98±1.57)nmol/L,compared with the control group(16.13±3.33)IU/L,(5.75±1.11)U/L,and(6.74±1.46)nmol/L,the difference was not statistically significant(t=0.140,0.843,0.708,P=0.889,0.402,0.481).After treatment,the levels of luteinizing hormone,follicle-stimulating hormone,an

关 键 词：终止妊娠 药物保守治疗 手术 异位妊娠 影响 

分 类 号：R5[医药卫生—内科学]