MoS_(2)/Fe_(3)O_(4)/Au复合材料制备及多功能生物探针  

Preparation of MoS_(2)/Fe_(3)O_(4)/Au Composites and Multifunctional Biological Probes

作　　者：张婷[1] 吉于今 楚学影[1] ZHANG Ting;JI Yujin;CHU Xueying(School of Physics,Changchun University of Science and Technology,Changchun 130022)

机构地区：[1]长春理工大学物理学院,长春130022

出　　处：《长春理工大学学报（自然科学版）》2022年第4期1-6,共6页Journal of Changchun University of Science and Technology(Natural Science Edition)

基　　金：教育部“111”创新引智项目(D17017);吉林省科技发展计划项目(202002040JC,20200201266JC)。

摘　　要：采用拉曼光谱分析复合前后样品的拉曼特性,发现引入Fe_(3)O_(4)纳米粒子后MoS_(2)的E^(1)_(2g)和A_(1g)拉曼振动峰红移,进一步引入Au纳米粒子后拉曼散射强度得到有效增强。磁学性质分析表明MoS_(2)/Fe_(3)O_(4)/Au复合材料无剩磁、无矫顽力,具有超顺磁性。复合材料与人IgG分子偶联后样品的傅里叶变换红外(FTIR)光谱中可以观察到酰胺键及-S-S-键等生物基团,表明可基于该复合材料构建生物探针。对比实验表明,生物分子偶联未影响复合材料拉曼光谱,且此生物探针在1.2 T磁场强度下1 min内即可富集。因此,该多功能材料可作为各类病原体的早期快速诊断的候选材料。Raman spectroscopy was used to analyze the Raman characteristics of the samples before and after recombination.After compounding Fe_(3)O_(4) nanoparticles,t he E^(1)_(2g) and A_(1g) peak positions of MoS_(2) shifted red,and the Raman peak intensity was effectively enhanced after compounding Au.The analysis of magnetic properties shows that MoS_(2)/Fe_(3)O_(4)/Au composites have no remanence,coercivity and super-paramagnetic.After the composite was coupled with human IgG molecule,biological groups such as amide bond and-S-S-bond could be observed in the Fourier transform infrared(FTIR)spectrum of the samples.It shows that the biological probes can be constructed based on the composite.Comparative experiments show that bio-molecular coupling does not affect the Raman spectra of the composites,and the biological probes can be enriched within 1 min under the magnetic field intensity of 1.2 T.Therefore,t he multifunctional material can be used as a candidate material for early,r apid and diagnosis of various pathogens.

关 键 词：多功能 贵金属 超顺磁性纳米粒子 过渡金属 抗体 

分 类 号：O469[理学—凝聚态物理]