金铃芍药散间歇服药法治疗湿热瘀结型慢性盆腔炎的临床研究  

Clinical study on the treatment of chronic pelvic inflammatory disease of damp-heat stasis type with Jinling Shaoyao powder

作　　者：莫小宇 谢宜燕 崔雪芳 Mo Xiaoyu;Xie Yiyan;Cui Xuefang(Department of Gynecology,Zhongshan Chenxinghai Hospital,Zhongshan 528415,China)

机构地区：[1]中山陈星海医院妇科,中山528415

出　　处：《国际医药卫生导报》2022年第22期3168-3171,共4页International Medicine and Health Guidance News

基　　金：中山市医学科研项目(2019A020415)。

摘　　要：目的观察分析金铃芍药散间歇服药法治疗湿热瘀结型慢性盆腔炎(CPID)的临床效果。方法选择2020年3月至2021年12月期间中山陈星海医院收治的CPID患者129例进行研究,并随机分为3组,各43例。对照A组年龄(34.73±8.79)岁,给予金铃芍药散治疗;对照B组年龄(33.98±8.91)岁,给予中成药“宫炎平片”治疗;观察组年龄(34.89±8.64)岁,给予自拟中药金铃芍药散间歇服药治疗。比较各组临床效果及安全性。采用独立样本t检验、χ^(2)检验。结果治疗30 d后,观察组综合疗效总有效率为95.35%(41/43)与对照A组[93.02%(40/43)]、对照B组[90.70%(39/43)]比较,差异均无统计学意义(χ^(2)=0.212、0.717,P=0.474、0.801)。治疗30 d后,观察组体征疗效总有效率为97.67%(42/43)与对照A组[95.35%(41/43)]、对照B组[93.02%(40/43)]比较,差异均无统计学意义(χ^(2)=0.345、1.048,P=0.590、0.127)。观察组不良反应发生率为4.65%(2/43)与对照A组[25.58%(11/43)]、对照B组[23.26%(10/43)]比较,差异均有统计学意义(χ^(2)=7.704、6.519,均P<0.001)。结论金铃芍药散间歇服药法治疗湿热瘀结型CPID与对照A组及对照B组疗法具有同等的临床治疗效果,且相比之下较对照A组及对照B组疗法可以显著减少患者经济负担,提高患者生活质量,节约药品资源,有效降低了临床服用胃肠道不良反应,具有良好的安全性,值得临床大力推广应用。Objective To observe,evaluate,and analyze the clinical effect of Jinling Shaoyao powder intermittently used in the treatment of chronic pelvic inflammatory disease(CPID)of damp-heat and blood stasis type.Methods A total of 129 patients with CPID admitted to Zhongshan Chenxinghai Hospital from March 2020 to December 2021 were selected,and were randomly divided into three groups with 43 patients in each group.The control group A was(34.73±8.79)years old and was treated with Jinling Shaoyao powder,the control group B was(33.98±8.91)years old and was treated with Chinese patent medicine"Gongyanping tablets",and the observation group was(34.89±8.64)years old and was treated with Jinling Shaoyao powder,a self-made Chinese medicine,intermittently.The clinical effects and safety of each group were compared.Independent sample t test andχ^(2) test were used.Results After 30 days of treatment,there were no statistically significant differences in the total effective rate of comprehensive curative effect between the observation group and the control group A and B[95.35%(41/43)vs.93.02%(40/43),90.70%(39/43)](χ^(2)=0.212,0.717;P=0.474,0.801).After 30 days of treatment,there were no statistically significant differences in the total effective rate of physical signs between the observation group and the control group A and B[97.67%(42/43)vs.95.35%(41/43),93.02%(40/43)](χ^(2)=0.345,1.048;P=0.590,0.127).There were statistically significant differences in the incidence of adverse reactions between the observation group and the control group A and B[4.65%(2/43)vs.25.58%(11/43),23.26%(10/43)](χ^(2)=7.704,6.519;both P<0.001).Conclusion Jinling Shaoyao powder used intermittently to treat CPID of damp-heat and blood stasis type has the same clinical treatment effect as the treatment methods of the control group A and B,and compared with the treatment methods of the control group A and B,it can significantly reduce the patients'economic burden,improve their quality of life,save the drug resources,effectively reduce the adverse gas

关 键 词：慢性盆腔炎 金铃芍药散 间歇服药 宫炎平片 

分 类 号：R271.9[医药卫生—中西医结合]