从阳虚寒凝论治冠状动脉微血管疾病  

Treating CMVD from Yang Deficiency and Cold Coagulation

作　　者：宋博策 谢蓓莉 别玉龙 刘明旺 闫宇新 张洋芳 李浩浩 赵福海[1,2] SONG Boce;XIE Beili;BIE Yulong;LIU Mingwang;YAN Yuxin;ZHANG Yangfang;LI Haohao;ZHAO Fuhai(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;National Clinical Research Center for Cardiovascular Diseases,Beijing 100091,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院西苑医院心血管科,北京100091 [2]国家中医心血管病临床医学中心,北京100091 [3]北京中医药大学,北京10029

出　　处：《中医药学报》2022年第11期1-4,共4页Acta Chinese Medicine and Pharmacology

基　　金：国家自然科学基金面上项目(81973674);北京市自然科学基金面上项目(7202175);中国中医科学院科技创新工程(CI2021A00901)。

摘　　要：冠状动脉微血管疾病(CMVD)作为缺血性心脏病的主要类型,因其发病率较高而广泛受到临床关注。CMVD属中医学“胸痹”“真心痛”范畴,但其发病机制尚不明确,且硝酸酯类、曲美他嗪等传统抗心绞痛药物治疗效果不佳,因此CMVD的相关研究逐渐成为心血管疾病领域的研究热点。本文通过整理胸痹相关医籍,结合陈可冀院士“三通两补”思想中的芳香温通疗法,从阳虚寒凝、络脉瘀阻的角度对CMVD进行进一步阐述,探索其病因病机和治疗规律,以期为CMVD的临床防治提供理论依据。Coronary microvascular disease(CMVD),as the main type of ischemic heart disease,has attracted widespread clinical attention due to its high incidence.CMVD belongs to the category of‘Chest Bi’and‘Real Heart Pain’in TCM,but its pathogenesis is still unclear,and traditional anti-angina drugs,such as Nitrates and Trimetazidine,are not effective.Therefore,related research on CMVD has gradually become a research hotspot in the field of cardiovascular diseases.It further elaborated CMVD from the perspective of Yang deficiency and cold coagulation,and collateral stasis,by carefully reading the relevant medical books of Chest Bi,combined with warming and activating method with aromatic herbs of academician CHEN Keji’s thought of‘three activating and two tonifying’,and it explored its etiology,pathogenesis and treatment rules,in order to provide theoretical basis for the clinical prevention and treatment of CMVD.

关 键 词：冠状动脉微血管疾病 微血管性心绞痛 阳虚寒凝 络脉瘀阻 芳香温通 

分 类 号：R256.22[医药卫生—中医内科学]