不同亚型子痫前期患者母儿结局分析  

Analysis of maternal and fetal outcomes in different subtype of preeclampsia

作　　者：杜培丽[1] 孙雯[1] 苏春宏[1] 张春芳[1] 余琳[1] 贺芳[1] 杜丽丽[1] 陈兢思[1] 陈敦金[1] Du Peili;Sun Wen;Su Chunhong;Zhang Chunfang;Yu Lin;He Fang;Du Lili;Chen Jingsi;Chen Dunjin(Department of Obstetrics and Gynecology,Third Affiliated Hospital of Guangzhou Medical University,Guangdong Province Key Laboratory of Major Obstetric Diseases,Guangzhou Medical Center for Critical Pregnant Women,Guangzhou 510515,China)

机构地区：[1]广州医科大学附属第三医院妇产科,广东省产科重大疾病重点实验室,广州重症孕产妇救治中心,510105

出　　处：《中华产科急救电子杂志》2022年第1期33-37,共5页Chinese Journal of Obstetric Emergency（Electronic Edition）

基　　金：国自然科学基金重点项目(81830045)。

摘　　要：目的分析不同亚型子痫前期患者的母儿结局。方法回顾性分析2009年1月1日至2019年12月31日在广州医科大学附属第三医院分娩的2960例单胎子痫前期患者早产组与足月产组、早发型组与晚发型组的临床资料及母儿结局。结果(1)母亲结局:①早产组与足月产组剖宫产率分别为(80.85%vs 61.67%,χ^(2)=1.327)、入住重症监护病房率(11.84%vs 2.25%,χ^(2)=86.844),P值均<0.05;②早发型与晚发型剖宫产率分别为(77.61%vs 70.30%,χ^(2)=1.327,P<0.05)、入住重症监护病房率(13.00%vs 4.55%,χ^(2)=69.158,P<0.05)。(2)新生儿结局:①早产组与足月产组在新生儿出生平均体重[(1472.19±673.50)g与(3067.49±523.92)g,Z=-42.4],活产比例(81.35%vs 99.31%,χ^(2)=2.204),新生儿窒息率(6.39%vs 0.79%,χ^(2)=53.51)P均<0.05。②早发型组与晚发型组新生儿出生体重[(1169.53±482.39)g vs(2765.37±683.22)g,Z=-43.895],活产比例(74.64%vs 98.31%,χ^(2)=3.926),新生儿窒息率(8.71%vs 1.31%,χ^(2)=86.82),差异均有统计学意义(P<0.05)。结论子痫前期患者早产组与足月产组相比,早产组母体及新生儿结局均较差。早发型与晚发型子痫前期相比,早发型母儿结局均较差。Objective To analyze the maternal and neonatal outcomes of patients with different subtype of preeclampsia.Methods A retrospective analysis was performed on the clinical data and maternal and infant outcomes of 2960 singleton patients with or without early-onset/late onset preeclampsia,who delivered from January 1,2009 to December 31,2019 in the Third Affiliated Hospital of Guangzhou Medical University.Results(1)Maternal outcomes:①Compared with the preterm preeclampsia group and term preeclalmpsia group,the rates of cesarean section were 80.85%and 61.67%,respectively(χ^(2)=1.327),the rates of admission to the intensive care unit was respectively 11.84%and 2.25%(χ^(2)=86.844);②The rates of early-onset preeclampsia and late-onset preeclampsia cesarean section was 77.61%and 70.30%,respectively(χ^(2)=1.327,P<0.05).Admission rate of intensive care unit was 13.00%and 4.55%,respiectively in early-onset group and late-onset group(χ^(2)=69.158,P<0.05).(2)Neonatal outcomes:①The mean birth weight of newborns was respectively(1472.19±673.50)g and(3067.49±523.92)g(Z=-42.4),the proportion of live births was respectively 81.35%and 99.31%comparing in early-onset group and late-onset group(χ^(2)=2.204).The rate of neonatal asphyxia was 6.39%and 0.79%,respectively in two groups(χ^(2)=53.51,all P<0.05).②Neonatal birth weight in early-onset group and late-onset group was respectively(1169.53±482.39)g and(2765.37±683.22)g(Z=-43.895),live birth ratio was 74.64%and 98.31%(χ^(2)=3.926),the rate of neonatal asphyxia was 8.71%and 1.31%,comparing in the two groups(χ^(2)=86.82).The difference was statistically significant(P<0.05).Conclusions Compared with preterm preeclampsia and term preeclampsia,the maternal and neonatal outcomes were worse in preterm preeclampsia.Compared with the late-onset group,maternal and child outcomes were worse in the early-onset group.

关 键 词：子痫前期 孕龄 妊娠结局 

分 类 号：R714.244[医药卫生—妇产科学]