加味消髓化核汤联合苍龟探穴法针刺治疗气滞血瘀证椎间盘突出症的临床研究  

Clinical Study of Jiawei Xiaosui Huahe Decoction Combined with Acupuncture Method of Canggui Tanxue in the Treatment of Lumbar Disc Herniation with Qi Stagnation and Blood Stasis Syndrome

作　　者：邓辉 乔红 DENG Hui;QIAO Hong(Dept.of Traditional Chinese Medicine Pharmacy,Suzhou Hospital Affiliated to Anhui Medical University,Anhui Suzhou 234000,China;Dept.of Traditional Chinese Medicine,Suzhou Hospital Affiliated to Anhui Medical University,Anhui Suzhou 234000,China)

机构地区：[1]安徽医科大学附属宿州医院中药科,安徽宿州234000 [2]安徽医科大学附属宿州医院中医科,安徽宿州234000

出　　处：《中国医院用药评价与分析》2022年第10期1172-1174,共3页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：安徽省中医药传承创新科研项目(No.2020ccyb23)。

摘　　要：目的:探讨加味消髓化核汤联合苍龟探穴法针刺治疗气滞血瘀证椎间盘突出症(LDH)的临床疗效。方法:将2020年2月至2022年1月在该院就诊的100例气滞血瘀证LDH患者随机分为对照组、观察组,各50例。对照组患者口服中药加味消髓化核汤治疗,观察组患者口服中药加味消髓化核汤联合苍龟探穴法针刺治疗。比较两组患者临床疗效、视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)和中医证候积分,以及血清炎症因子水平[肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)和降钙素原(PCT)]的差异。结果:观察组患者的治疗总有效率高于对照组[96.00%(48/50)vs. 76.00%(38/50)],差异有统计学意义(P<0.05)。治疗后,观察组患者的VAS评分、ODI指数和中医证候积分,TNF-α、hs-CRP和PCT水平明显低于对照组,差异均有统计学意义(P<0.05)。结论:加味消髓化核汤联合苍龟探穴法针刺治疗气滞血瘀证LDH的效果较好,可减轻患者的腰腿疼痛症状,改善腰椎功能障碍,降低炎症反应。OBJECTIVE: To probe into the clinical efficacy of Jiawei Xiaosui Huahe decoction combined with acupuncture method of Canggui Tanxue in the treatment of lumbar disc herniation(LDH) with Qi stagnation and blood stasis syndrome. METHODS: A total of 100 LDH patients with Qi stagnation and blood stasis syndrome admitted into the hospital from Feb. 2020 to Jan. 2022 were randomly divided into the control group(n=50) and the observation group(n=50). The control group was given oral Jiawei Xiaosui Huahe decoction, while the observation group received oral Jiawei Xiaosui Huahe decoction combined with acupuncture method of Canggui Tanxue. The clinical efficacy, visual analogue score(VAS), Oswestry dysfunction index(ODI) and TCM syndrome scores, inflammatory factors such as tumor necrosis factor-α(TNF-α), high sensitivity C-reactive protein(hs-CRP) and procalcitonin(PCT) were compared between two groups. RESULTS: The total effective rate of the observation group was higher than that of the control group [96.00%(48/50) vs. 76.00%(38/50)], the difference was statistically significant(P<0.05). After treatment, the VAS scores, ODI, TCM syndrome scores, TNF-α, hs-CRP and PCT levels in the observation group were significantly lower than those in the control group, the differences were statistically significant(P<0.05). CONCLUSIONS: The efficacy of Jiawei Xiaosui Huahe decoction combined with acupuncture method of Canggui Tanxue in the treatment of LDH with Qi stagnation and blood stasis syndrome is significant, which can significantly improve the symptoms of back and leg pain and lumbar dysfunction, and reduce inflammatory reaction.

关 键 词：加味消髓化核汤 苍龟探穴法针刺 椎间盘突出症 

分 类 号：R932[医药卫生—生药学]