胶原透明质酸敷料用于痤疮凹陷性瘢痕点阵铒激光术后的临床观察  

Application of collagen and hyaluronic acid dressing in erbium fractionated laser for the treatment of atrophic facial acne scars

作　　者：王一臣 蒋冠 WANG Yichen;JIANG Guan(Department of Dermatology,Xuzhou Central Hospital,Xuzhou Clinical College,Xuzhou Medical University,Xuzhou,Jiangsu 221009,China;Department of Dermatology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221002)

机构地区：[1]徐州市中心医院皮肤科,徐州医科大学徐州临床学院,江苏徐州221009 [2]徐州医科大学附属医院皮肤科,江苏徐州221002

出　　处：《徐州医科大学学报》2022年第9期682-685,共4页Journal of Xuzhou Medical University

摘　　要：目的观察胶原透明质酸敷料用于痤疮凹陷性瘢痕术后的修复效果。方法选择46例痤疮凹陷性瘢痕患者,随机分为实验组和对照组,每组各23例。实验组在点阵铒激光治疗后外用胶原透明质酸敷料20 min,共7 d,对照组用纱布湿敷,其余治疗相同。治疗后随访3个月,观察术后急性炎症反应情况、结痂脱落时间、患者自我舒适度评价、VISIA皮肤检测仪评价红色区域、疗程后色素沉着率、渗出性创面恢复情况及其他不良反应的发生情况。结果实验组术后急性炎症反应评分、自我舒适度评价优于对照组(P<0.05),色素沉着率、结痂脱落时间、VISIA下红色区域评分均低于对照组(P<0.05)。结论痤疮凹陷性瘢痕点阵铒激光术后应用新型胶原透明质酸敷料可加快激光术后红斑恢复,缩短创面愈合、结痂脱落时间,提高术后舒适度。Objective To evaluate the application of collagen and hyaluronic acid dressing in erbium fractionated laser for the treatment of atrophic facial acne scars.Methods A total of 46 patients with atrophic facial acne scars were divided into two groups(n=23):an experimental group and a control group.The experimental group underwent erbium fractionated laser followed by external application of collagen and hyaluronic acid dressing within 20 min for seven days.In contrast,the control group was covered with saline-soaked gauze,while other treatments were the same.The patients were followed up for three months,while their acute inflammatory response,scab shedding time,patient comfort,the incidence of hyperpigmentation,the red areas assessment with VISIA skin tester,and other adverse reactions were assessed.Results The experimental group showed improvement in acute inflammatory response score and patient comfort(P<0.05),as well as decreases in scab shedding time,the incidence of hyperpigmentation,and the red area score under VISIA,compared with the control group(P<0.05).Conclusions Application of new collagen and hyaluronic acid dressing in erbium fractionated laser for atrophic facial acne scars can fasten the recovery of postoperative skin erythema,shorten scab shedding time,accelerate wound healing,and improve patient comfort.

关 键 词：痤疮 瘢痕 胶原透明质酸 铒激光 点阵 

分 类 号：R751.05[医药卫生—皮肤病学与性病学]