鼻腔冲洗在慢性鼻窦炎术后应用疗效分析  

Analysis of the application effect of nasal irrigation on postoperative chronic sinusitis

作　　者：杨欢欢 李新玉 杨旭东[1] Yang Huanhuan;Li Xinyu;Yang Xudong(Department of otolaryngology,affiliated hospital of Jiangsu University,Zhenjiang,Jiangsu,212001,China)

机构地区：[1]江苏大学附属医院耳鼻喉科,江苏镇江212001

出　　处：《齐齐哈尔医学院学报》2022年第17期1643-1646,共4页Journal of Qiqihar Medical University

摘　　要：目的探讨鼻腔冲洗在慢性鼻窦炎术后应用疗效。方法选择2019年1月—2020年12月本院收治的100例慢性鼻窦炎手术患者为研究对象,依据随机抽签法分为对照组和观察组两组,每组各50例。对照组以口服克拉霉素缓释片及曲安奈德鼻喷剂治疗,观察组予以口服克拉霉素缓释片及曲安奈德鼻喷剂联合鼻腔冲洗治疗。比较两组鼻内镜Lund-Kennedy评分、SNOT-20评分、MTR、sIgA以及并发症。结果治疗前,两组鼻内镜Lund-Kennedy评分、SNOT-20评分比较,差异无统计学意义(P>0.05);治疗后,观察组鼻内镜Lund-Kennedy评分、SNOT-20评分均低于对照组(P<0.05)。治疗前,两组MTR、sIgA比较,差异无统计学意义(P>0.05),治疗后,观察组MTR、sIgA均高于对照组(P<0.05)。治疗后,观察组出现鼻泪管阻塞、鼻腔黏连、嗅觉减退、鼻腔出血的总发生率(6.00%)低于对照组(20.00%)(χ^(2)=4.332,P<0.05)。结论鼻腔冲洗在慢性鼻窦炎术后效果显著,改善鼻腔内部症状,提升鼻内镜Lund-Kennedy评分及生活质量,改善鼻黏膜纤毛传输速率以及免疫球蛋白A浓度,降低并发症发生率,利于患者病情好转,值得推广。Objective To investigate the application effect of nasal irrigation on postoperative chronic sinusitis.Methods 100 patients suffered with chronic sinusitis those under surgery in our hospital from January 2019 to December 2020 were selected as the research objects.They were randomly divided into control group(n=50 cases)and observation group(n=50 cases).Patients in the control group was treated with clarithromycin sustained-release tablets and the triamcinolone acetonide nasal spray,and patients in the observation group were treated with clarithromycin sustained-release tablets and the triamcinolone acetonide nasal spray combined with nasal irrigation.Lund-Kennedy score,SNOT-20 score,MTR,SIgA and complications were compared between the two groups.Results Before treatment,there were no significant difference in Lund-Kennedy score and SNOT-20 score between the two groups(P>0.05).After treatment,Lund-Kennedy score and SNOT-20 score of nasal endoscopy in the observation group were lower than those in the control group(P<0.05).Before treatment,there were no significant difference in MTR and sIgA between the two groups(P>0.05).After treatment,MTR and sIgA in the observation group were higher than those in the control group(P<0.05).After treatment,the total incidence of nasolacrimal duct obstruction,nasal adhesion,anosmia and nasal bleeding in the observation group was 6.00%,which was lower than 20.00% in the control group(χ^(2)=4.332,P<0.05).Conclusions Nasal irrigation has a significant effect after the operation of chronic sinusitis.It could improve the internal symptoms of nasal cavity,improve the Lund-Kennedy score of nasal endoscopyand quality of life,improve the ciliary transmission rate of nasal mucosa and the concentration of immunoglobulin A,reduce the incidence of complications,and is conducive to the improvement of patients’condition,which is worthy of promotion.

关 键 词：鼻腔冲洗 慢性鼻窦炎 生活质量 并发症 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]