Neurotoxicity due to dimethylamine borane poisoning via skin absorption:a case report  

作　　者：Guang-cai Yu Ya-qian Li Tian-zi Jian Bao-tian Kan Si-qi Cui Ping Han Xiang-dong Jian 

机构地区：[1]Department of Poisoning and Occupational Diseases,Emergency Medicine,Qilu Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan 250012,China [2]Shandong University of Traditional Chinese Medicine,Jinan 250012,China [3]Department of Geriatric Medicine,Qilu Hospital of Shandong University,School of Nursing,Cheeloo College of Medicine,Shandong University,Jinan 250012,China [4]School of Public Health,Cheeloo College of Medicine,Shandong University,Jinan 250012,China

出　　处：《World Journal of Emergency Medicine》2022年第6期500-503,共4页世界急诊医学杂志（英文）

基　　金：Scientific Research Project of Qilu Hospital,Shandong University(project no.KYLL-2019-296).

摘　　要：Dear editor,Dimethylamine borane(DMAB,CAS no.74-94-2),also called boron-dimethylamine complex,is a white crystalline solid.It has an amine odour under mild conditions.[1]As an excellent reducing agent,DMAB is widely used in the semiconductor industry,pharmaceutical manufacturing,[2]oligomer and polymer production,and hydrogen storage.[3]Acute DMAB exposure may cause eye or respiratory irritation,throat discomfort,vomiting,diarrhoea,and pulmonary oedema.[1,4]Isolated reports indicated that DMAB exposure causes acute cerebellar oedema and peripheral neuropathy.[1,5,6]Herein,we report a case of DMAB poisoning via dermal absorption in which the central and peripheral nervous systems were the primary sites of toxic injury.We highlight the use of brain magnetic resonance imaging(MRI)and electromyography(EMG)for evaluation after exposure.

关 键 词：conditions. ABSORPTION BORON 

分 类 号：R595[医药卫生—内科学]