基于肠道菌群探讨从脾论治2型糖尿病并骨质疏松症  

Based on the Intestinal Flora to Explore the Treatment of Type 2 Diabetes and Osteoporosis from the Spleen

作　　者：王晶[1] 王晓晖[2] 马欢欢 王亚萍 WANG Jing;WANG Xiaohui;MA Huanhuan;WANG Yaping(Gansu University of Traditional Chinese Medicine,Gansu Lanzhou 730000,China;Gansu Provincial Hospital of Traditional Chinese Medicine,Gansu Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃省中医院,甘肃兰州730050

出　　处：《中医药临床杂志》2022年第9期1592-1595,共4页Clinical Journal of Traditional Chinese Medicine

基　　金：甘肃省重点研发计划(21YF5FA022);兰州市人才创新创业项目(2021-RC-118)。

摘　　要：2型糖尿病合并骨质疏松症是继发于糖尿病的全身骨代谢性疾病,典型特征是骨脆性增加,早期可无明显临床表现,轻者可出现骨痛和骨骼变形,重者发生骨折。该病的发病率和致残率每年呈上升趋势,给患者家庭造成繁重负担。目前大量研究表明肠道菌群与众多慢性代谢性疾病的发生发展紧密联系,包括2型糖尿病、骨质疏松症等,而肠道菌群在机体中发挥的作用与中医理论中“脾”的生理功能有诸多相似之处,因此该文对肠道菌群、2型糖尿病并骨质疏松症与脾三者之间彼此的联系展开论述,立足于肠道菌群,以期为临床从脾论治2型糖尿病并骨质疏松症提供新思路。Type 2 diabetes mellitus complicated with osteoporosis is a systemic bone metabolic disease secondary to diabetes mellitus.The typical feature is increased bone fragility.There may be no obvious clinical manifestations in the early stage.Bone pain and bone deformation may occur in mild cases,and fractures may occur in severe cases.The incidence and morbidity of the disease are increasing every year,placing a heavy burden on the patient's family.At present,a large number of studies have shown that the intestinal flora is closely related to the occurrence and development of many chronic metabolic diseases,including type 2 diabetes,osteoporosis,etc.,and the role of the intestinal flora in the body is related to the role of the“spleen”in the theory of traditional Chinese medicine.There are many similarities in physiological functions,so this article discusses the relationship between the intestinal flora,type 2 diabetes and osteoporosis and the spleen.Provide new ideas for the treatment of type 2 diabetes and osteoporosis.

关 键 词：肠道菌群 2型糖尿病并骨质疏松症 脾 

分 类 号：R255.4[医药卫生—中医内科学]