超声微泡技术在动物实验的应用  

Application of ultrasound-stimulated microbubbles in zoopery

作　　者：王佩瑶 王灿 孙瑶琪 秦杨阳 黄猛[1,3] WANG Peiyao;WANG Can;SUN Yaoqi;QIN Yangyang;HUANG Meng(the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Chaohu Hospital of Anhui Medical University,Chaohu 238000;East District of First Affiliated Hospital of Anhui Medical University/Feidong People’s Hospital,Hefei 231600)

机构地区：[1]安徽医科大学第一附属医院,合肥230022 [2]安徽医科大学附属巢湖医院,安徽巢湖238000 [3]安徽医科大学第一附属医院东城院区/肥东县人民医院,合肥231600

出　　处：《中国实验动物学报》2022年第5期727-732,共6页Acta Laboratorium Animalis Scientia Sinica

基　　金：安徽医科大学第一附属医院东城院区/肥东县人民医院院内科研项目(Ky2022019)。

摘　　要：低频超声激发微泡技术在临床中的应用越来越常见,主要包括靶向输送药物、增强免疫治疗、介导基因转染、开放血脑屏障、损伤肿瘤血管、辅助血栓消融。本文总结了超声微泡的制备、超声微泡技术在动物实验的应用,旨在为临床超声微泡技术的实际应用提供理论参考。Ultrasound-stimulated microbubble technology is becoming increasingly more common in the clinical setting.Its uses mainly include targeted drug delivery,enhanced immunotherapy,gene transfection,opening of the bloodbrain barrier,damaging tumor blood vessels,and assisting in thrombus ablation.In this paper,the preparation of ultrasonic microbubbles and the application of ultrasonic microbubbles in zoopery are summarized with the aim of providing a theoretical reference for the practical application of ultrasonic microbubbles in clinical practice.

关 键 词：低频超声 微泡 制备 动物实验 

分 类 号：Q95-33[生物学—动物学]