自报职业性噪声暴露与肺功能水平的关联性研究  

Association between self-reported occupational noise exposure and lung function

作　　者：王欣[1] 汪洋 李连凤 王冬明[4] 陈卫红[4] 周婷[2,3] WANG Xin;WANG Yang;LI Lian-feng;WANG Dong-ming;CHEN Wei-hong;ZHOU Ting(Department of Health Education,Emergency Management,Nanshan District Center for Disease Control and Prevention,Shenzhen,Guangdong 518055,China;Department of Environmental Health and Occupational Medicine,School of Public Health,Wuhan University of Science and Technology,Wuhan,Hubei 430065,China;Hubei Province Key Laboratory of Occupational Hazard Identification and Control,Wuhan University of Science and Technology,Wuhan,Hubei 430030,China;School of Public Health,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China)

机构地区：[1]深圳市南山区疾病预防控制中心应急办健康教育科,广东深圳518055 [2]武汉科技大学公共卫生学院,湖北武汉430065 [3]武汉科技大学职业危害识别与控制湖北省重点实验室,湖北武汉430065 [4]华中科技大学同济医学院公共卫生学院,湖北武汉430030

出　　处：《公共卫生与预防医学》2022年第6期51-55,共5页Journal of Public Health and Preventive Medicine

基　　金：湖北省教育厅科学研究计划指导性项目(B2020016)。

摘　　要：目的分析自报职业性噪声暴露与人群肺功能水平变化之间的关系。方法采用调查问卷收集1009例社区健康居民和1009例成人哮喘患者的基本信息和职业接触史,测定其肺功能水平。采用多元线性回归分析自报职业性噪声暴露与肺功能水平的关系及生产性粉尘在其中的作用。结果与无职业性噪声暴露史的人群相比,自报有职业性噪声暴露史的健康居民FVC实际值降低0.22 L,处于急性发作期的哮喘患者FVC和FEV_(1)实际值分别显著降低0.39 L和0.31 L。当无生产性粉尘暴露史时,有职业性噪声暴露史的哮喘患者FVC、FEV_(1)、PEF水平显著低于无噪声暴露史的患者(P<0.05),且当患者处于持续发作期时,其FEV_(1)、PEF和FEV_(1)/FVC的实际值分别降低1.48 L、3.56 L/s和28.45%。若同时有生产性粉尘和噪声暴露史,健康居民FVC和PEF的水平分别显著降低0.25 L和0.77 L,但哮喘患者的肺功能水平无显著变化。结论自报职业性噪声暴露与健康居民以及哮喘患者肺功能下降均有关,且职业性噪声与粉尘联合暴露对健康居民肺功能的影响较为明显。Objective To analyze the relationship between self-reported occupational noise exposure and lung function in healthy residents and adult asthma patients.Methods The basic information,self-reported exposure history of noise and productive dust,and behavior and living habits of 1009 healthy community residents and 1009 adult asthma patients were collected and lung function of all subjects was measured.Multiple linear regression model was used to analyze the relationship between self-reported occupational noise exposure and lung function in heathy residents and asthma patients,and stratified analysis was used to analyze the influence of self-reported productive dust exposure on the association between self-reported occupational noise exposure and lung function.Results Compared with the population without self-reported occupational noise exposure,the actual value of FVC was decreased by 0.22 L in healthy residents with self-reported occupational noise exposure history,and the actual values of FVC and FEV_(1) in asthmatic patients with acute attack were significantly reduced by 0.39 L and 0.31 L,respectively.In populations without self-reported productive dust exposure,stratified analysis showed that the levels of FVC,FEV_(1) and PEF in asthma patients with self-reported occupational noise exposure were significantly lower than those without exposure(P<0.05).Furthermore,the actual values of FEV_(1),PEF and FEV_(1)/FVC were significantly decreased by 1.48 L,3.56 L/s and 28.45%when asthma patients were in a persistent attack stage,respectively.In populations with self-reported productive dust exposure,the levels of FVC and PEF were declined by 0.25 L and 0.77 in healthy residents with both self-reported both occupational noise and dust exposure,respectively.However,there was no significant difference of lung function in asthma patients whether or not with self-reported occupational noise exposure.Conclusion Self-reported occupational noise exposure is associated with declined lung function in heathy residents and asthma

关 键 词：自报职业性噪声暴露 自报生产性粉尘暴露 成人哮喘 肺功能 

分 类 号：R181[医药卫生—流行病学]