无创通气联合药物雾化吸入治疗AECOPD合并呼吸衰竭临床疗效观察  

Clinical Observation of Noninvasive Ventilation Combined with Drug Atomization Inhalation in the Treatment of AECOPD Complicated with Respiratory Failure

作　　者：田杨 TIAN Yang(Shenyang Fourth People’s Hospital,Liaoning Shenyang 110031)

机构地区：[1]沈阳市第四人民医院,辽宁沈阳110031

出　　处：《中国医疗器械信息》2022年第20期143-145,共3页China Medical Device Information

摘　　要：目的:观察BiPAP无创通气联合药物雾化吸入治疗AECOPD合并呼吸衰竭患者疗效。方法:选取2020年1月~2020年8月本院收治的AECOPD合并呼吸衰竭患者80例,按治疗措施分为两组,每组均进行常规治疗。对照组40例仅用BiPAP无创通气,研究组40例BiPAP无创通气下复方异丙托溴铵和布地奈德雾化吸入,对比两组疗效、血气分析、上机时间和住院时间,分析两组的气管插管与病死率情况。结果:研究组治疗总有效率(95%)高于对照组(62.5%),研究组PaCO_(2)、pH、R、PaO_(2)水平、呼吸频率显著优于对照组,研究组住院天数少于对照组,上机天数少于对照组,且研究组气管插管率低于对照组,病死率少于对照组,差异有统计学意义,P<0.05。结论:无创呼吸机联合药物雾化吸入能明显改善AECOPD合并呼吸衰竭患者疗效,对减少病死率和改善患者血气指标具有显著作用。Objective:To observe the effect of BiPAP noninvasive ventilation combined with drug atomization inhalation in the treatment of AECOPD patients with respiratory failure.Methods:80 cases of AECOPD patients with respiratory failure admitted to our hospital from January 2020 to August 2020 were selected and divided into two groups according to the treatment measures.Each group received routine treatment.The control group(40 cases)only used BiPAP noninvasive ventilation.The study group(40 cases)used BiPAP non-invasive ventilation to inhale compound ipratropium bromide and budesonide.The efficacy,blood gas analysis,time on the machine and hospital stay of the two groups were compared,and the tracheal intubation and mortality of the two groups were analyzed.Results:The total effective rate of treatment in the study group(95%)was higher than that of the control group(62.5%).The PaCO_(2),pH,R,PaO_(2) levels and respiratory rate in the study group were significantly better than those in the control group.Less than the control group,and the tracheal intubation rate of the study group was lower than that of the control group,and the fatality rate was lower than that of the control group,which was statistically significant,P<0.05.Conclusion:Non-invasive ventilator combined with drug atomization inhalation can significantly improve the efficacy of AECOPD patients with respiratory failure,and has a significant effect on reducing the mortality rate and improving the blood gas indicators of patients.

关 键 词：慢性阻塞性肺疾病急性加重期 呼吸衰竭 BIPAP无创通气 

分 类 号：R56[医药卫生—呼吸系统]