铜催化1,4-二炔硼质子化反应制备支链烯基硼化合物  

Regioselective synthesis of branched alkenylborons via coppercatalyzed protoborylation of 1,4-diynes

作　　者：孙欣悦 徐建林 李琦 马巍巍 徐允河[1] Xinyue Sun;Jianlin Xu;Qi Li;Weiwei Ma;Yunhe Xu(Department of Chemistry,University of Science and Technology of China,Hefei 230026,China)

机构地区：[1]中国科学技术大学化学系,安徽合肥230026

出　　处：《中国科学技术大学学报》2022年第10期31-41,67,共12页JUSTC

基　　金：supported by the Fundamental Research Funds f or the Central Universities (WK2060000017)

摘　　要：本文报道了铜催化1,4-二炔的高区域选择性硼质子化反应用于合成烯基硼类化合物。该反应对于各种(杂)芳基和烷基取代的末端1,4-二炔底物均能以较高的产率和区域选择性生成相应的产物,反应产物容易发生衍生化反应转化为多种有用的产物。A copper-catalyzed highly regioselective protoborylation of 1,4-diynes for the synthesis of alkenylboramide compounds was reported.Various(hetero)aryl and alkyl substituted terminal 1,4-diynes afforded the corresponding products in high yields and regioselectivities.The utility of alkenyl-B(dan)products was proven by their convenient deriv-atizations.

关 键 词：1 4-二炔 铜催化 硼质子化反应 区域选择性 α-烯基硼 

分 类 号：O622[理学—有机化学]