经桡动脉入径直接PCI联合替罗非班治疗ASTEMI的临床效果分析  

Clinical effect of transradial direct PCI combined with tirofiban in the treatment of ASTEMI

作　　者：崔殿全 CUI DianQuan(Department of Cardiology,Fengcheng Central Hospital,Fengcheng 118100,China)

机构地区：[1]辽宁省凤城市中心医院心内科,118100

出　　处：《中国实用医药》2022年第23期37-39,共3页China Practical Medicine

摘　　要：目的 探究经桡动脉入径直接经皮冠状动脉介入术(PCI)联合替罗非班治疗急性ST段抬高型心肌梗死(ASTEMI)的临床效果。方法 66例ASTEMI患者,随机分为A组和B组,每组33例。两组均行PCI联合替罗非班治疗, A组采用经股动脉入路PCI, B组采用经桡动脉入径直接PCI。对比两组的一次穿刺成功率、PCI成功率、术后TIMI血流分级及心血管不良事件发生率。结果 B组患者一次穿刺成功率、PCI成功率分别为96.97%、100.00%,均高于A组的75.76%、72.73%,差异具有统计学意义(P<0.05);B组患者术后TIMI血流分级优于A组,差异具有统计学意义(P<0.05)。B组患者心血管不良事件发生率为12.12%,低于A组的36.36%,差异具有统计学意义(P<0.05)。结论 经桡动脉入径直接经PCI联合替罗非班治疗ASTEMI的临床效果显著,可有效降低心血管不良事件发生率,促进患者康复。Objective To investigate the clinical effect of transradial direct percutaneous coronary intervention(PCI)combined with tirofiban in the treatment of acute ST segment elevation myocardial infarction(ASTEMI).Methods A total of 66 patients with ASTEMI were randomly divided into group A and group B,with 33 cases in each group.Both groups received PCI combined with tirofiban.Group A received transfemoral PCI,and group B received transradial direct PCI.The success rate of one-time puncture,PCI success rate,postoperative TIMI blood flow classification and the incidence of cardiovascular adverse events were compared between the two groups.Results The success rate of one-time puncture and PCI in group B were 96.97%and 100.00%,which were higher than 75.76%and 72.73%in group A,and the differences were all statistically significant(P<0.05).The postoperative TIMI blood flow classification in group B was better than that in group A,and the difference was statistically significant(P<0.05).The incidence of cardiovascular adverse events in group B was 12.12%,which was lower than 36.36%in group A,and the difference was statistically significant(P<0.05).Conclusion Transradial direct PCI combined with tirofiban has significant clinical effect in the treatment of ASTEMI,which can effectively reduce the rate of cardiovascular events and promote rehabilitation of patients.

关 键 词：经桡动脉入径 直接经皮冠状动脉介入术 替罗非班 急性ST段抬高型心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]