双源CT灌注成像在甲状腺良恶性结节诊断中的价值  

The Value of Dual-source CT Perfusion Imaging in the Diagnosis of Benign and Malignant Thyroid Nodules

作　　者：冀春亮[1] 陈正光[1] 李默[1] JI Chun-liang;CHEN Zheng-guang;LI Mo(Department of Radiology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)

机构地区：[1]北京中医药大学东直门医院放射科,北京100700

出　　处：《中国CT和MRI杂志》2022年第11期46-48,共3页Chinese Journal of CT and MRI

基　　金：教育部直属高校青年教师项目(2019-JYB-JS-063)。

摘　　要：目的研究双源CT灌注成像(DSCTPI)在甲状腺良恶性结节鉴别诊断中的应用价值。方法搜集甲状腺良性结节患者50例,甲状腺癌患者30例。2组患者均进行DSCTPI检查,测量并分析比较2组中病变组织与正常组织以及良恶性组之间的血流量(BF)、血容量(BV)、表面通透性(PS)、平均通过时间(MTT)及峰值时间(TTP)灌注参数比值。结果良性组与对侧正常组织的BF、BV、PS、MTT、TTP灌注参数值差异较小,比值较大,差异无统计学意义(P﹥0.05);恶性组与对侧正常组织、良恶性组之间的PS灌注参数值差异较大,比值较小,恶性组PS值明显低于正常组织以及良性组,差异有统计学意义(P﹤0.05)。结论CT灌注成像在良恶性结节鉴别诊断中有临床应用价值。Objective To explore the value of dual-source CT perfusion imaging(DSCTPI)in the differential diagnosis of benign and malignant thyroid nodules.Methods 50 patients with thyroid nodules were selected as benign group,and 30 patients with thyroid cancer were selected as malignant group.The patients in both groups were examined by DSCTPI,and the blood flow(BF),blood volume(BV),surface permeability(PS),and average passage time between the diseased and normal tissues and the benign and malignant groups in the two groups were measured and analyzed.(MTT)and peak time(TTP)perfusion parameter values.Results BF,BV,PS,MTT,TTP perfusion parameter values of benign group and normal tissue were smaller,the ratio was larger,the difference was not statistically significant(P﹥0.05);between malignant group and normal tissue,benign and malignant group The values of PS perfusion parameters are large and the ratio is small.The PS value of malignant group is significantly lower than that of normal tissue and benign group,the difference is statistically significant(P﹤0.05).Conclusion CT perfusion imaging is of clinical value in the differential diagnosis of benign and malignant nodules.

关 键 词：甲状腺 灌注成像 体层摄影术 

分 类 号：R816.6[医药卫生—放射医学]