875例儿童食物特异性IgG抗体检测结果分析  

Analysis of food specific IgG antibody in 875 children

作　　者：崔敏 林宏 王青波 CUI Min;LIN Hong;WANG Qingbo(New Century International Children’s Hospital,Beijing 100045,China;Beijing Rectum Hospital,Beijing 100120,China)

机构地区：[1]北京新世纪儿童医院检验科,北京100045 [2]北京市肛肠医院检验科,北京100120

出　　处：《医药前沿》2022年第25期36-38,42,共4页Journal of Frontiers of Medicine

摘　　要：目的:对疑似食物不耐受疾病血清样本特异性抗体检测结果进行分析,初步了解儿童食物不耐受种类和特点,为疾病预防和儿童饮食计划制定提供参考。方法:选取2017年1月—2021年12月北京新世纪儿童医院收治的896例患儿。采用酶联免疫吸附试验(ELISA)检测患儿血清中14种食物(牛肉、鸡肉、猪肉、鳕鱼、玉米、螃蟹、虾、鸡蛋、牛奶、蘑菇、大米、小麦、大豆、西红柿)中的特异性IgG(sIgG)抗体。结果:896份血清中,875份血清sIgG阳性,阳性率97.7%。鸡蛋(88.46%)、牛奶(83.20%)、小麦(55.43%)、西红柿(44.23%)sIgG阳性率较高,猪肉(2.86%)、牛肉(2.17%)sIg G阳性率较低。不同年龄组鸡蛋、小麦、西红柿、大豆、大米、虾、牛肉sIgG阳性率比较,差异有统计学意义(P<0.05)。不同性别s I g G阳性率比较,差异无统计学意义(P>0.05)。结论:北京新世纪儿童医院就诊儿童不耐受食物主要是鸡蛋和牛奶,其次是小麦、西红柿,不同年龄段不耐受食物存在显著差异,儿童饮食计划制定过程中应根据个体差异制定科学的个体饮食计划,有效规避不耐受食物,保证儿童健康成长。Objective To Analysis of specific antibody test results of serum samples,we can preliminarily understand the types and characteristics of children’s food intolerance,so as to provide reference for disease prevention and children’s diet planning.Methods Food specific IgG antibody detection kit produced by American biomeric company,14 kinds of food specific IgG(sIgG)antibodies(beef,chicken,pork,COD,corn,crab,shrimp,egg,milk,mushroom,rice,wheat,soybean and tomato)in children’s serum were detected by ELISA.Results 875 sera were sIgG positive among 896 sera,with a positive rate of 97.7%.The positive rates of sIgG in eggs(88.46%),milk(83.20%),wheat(55.43%)and tomatoes(44.23%)were higher.The positive rates of sIgG in pork(2.86%)and beef(2.17%)were low.The sIgG positive rate of eggs,wheat,tomatoes,soybeans,rice,shrimp and beef were significantly in different age groups(P<0.05).There was no significant difference between different sexes.Conclusion The intolerable foods of children in NCICH are mainly eggs,milk,wheat and tomatoes.The positive rates of sIgG were significantly in different age groups.Formulate a scientific individual diet plan to effectively avoid intolerable food and ensure the healthy growth of children.

关 键 词：食物不耐受 特异性IGG 儿童 

分 类 号：R725[医药卫生—儿科]