^(18)F-FDG PET/CT在CT引导下经皮穿刺肺活检术中的增益价值  

THE GAIN VALUE OF^(18)F-FDG PET/CT IN CT-GUIDED PERCUTANEOUS LUNG BIOPSY

作　　者：周大鹏[1] 纪伟仙 王刚[3] 胡效坤[1] 于华龙[3] 盛玉龙 ZHOU Dapeng;JI Weixian;WANG Gang;HU Xiaokun;YU Hualong;SHENG Yulong(Department of Interventional Medicine,the Affiliated Hospital of Qingdao University,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院介入医学科,山东青岛266003 [2]青岛市城阳人民医院放射科 [3]青岛大学附属医院放射科

出　　处：《青岛大学学报（医学版）》2022年第5期720-725,共6页Journal of Qingdao University(Medical Sciences)

基　　金：中国医药教育协会2020重大科学攻关问题和医药技术难题科研课题(2020KTZ003)。

摘　　要：目的探讨^(18)F-FDG PET/CT图像在CT引导下经皮穿刺肺活检术中的增益价值。方法回顾性分析行CT及PET/CT引导穿刺的286例肺部病变,穿刺靶点选择参照^(18)F-FDG PET/CT图像放射性核素浓聚情况。以病理或临床随访结果为标准,分别计算以放射性浓聚点(A组)和非浓聚点(B组)作为活检取材点的诊断准确率、灵敏度和特异度。结果A组诊断准确率为97.9%,灵敏度为97.5%,特异度为100.0%;B组诊断准确率为92.3%,灵敏度为90.9%,特异度为100.0%。两组诊断准确率和灵敏度比较差异有统计学意义(χ^(2)=6.125、3.372,P<0.05)。结论以^(18)F-FDG PET/CT图像放射性浓聚点作为穿刺靶区,可以提高诊断准确率及灵敏度,具有增益价值。Objective To investigate the gain value of^(18)F-FDG PET/CT image in CT-guided percutaneous lung biopsy.Methods A retrospective analysis was performed for 286 patients with pulmonary lesions who underwent CT and PET/CT-guided puncture,and the puncture target was selected based on the concentration of radionuclides on^(18)F-FDG PET/CT image.With the pathological or clinical follow-up results as the standard,diagnostic accuracy,sensitivity,and specificity were calculated for the samples collected at radioactive concentration point(group A)or non-concentration point(group B).Results Group A showed a diagnostic accuracy of 97.9%,a sensitivity of 97.5%,and a specificity of 100.0%,while group B had a diagnostic accuracy of 92.3%,a sensitivity of 90.9%,and a specificity of 100.0%.There were significant differences in diagnostic accuracy and sensitivity between the two groups(χ^(2)=6.125,3.372;P<0.05).Conclusion The puncture target area selected based on the radioactive concentration points on^(18)F-FDG PET/CT image can improve diagnostic accuracy and sensitivity and has gain value.

关 键 词：正电子发射断层显像术 氟脱氧葡萄糖F18 体层摄影术 X线计算机 活组织检查 针吸 肺疾病 

分 类 号：R445.5[医药卫生—影像医学与核医学] R446.8[医药卫生—诊断学]