基于QCT测量腹腔内脏脂肪面积与腹主动脉钙化的相关性研究  

Correlation of visceral adipose tissue and abdominal aortic calcification based on quantitative computed tomography

作　　者：王诚明 徐志锋[1] 麦长立 熊伟翔 潘爱珍[1] WANG Cheng-ming;XU Zhi-feng;MAI Chang-li(Department of Medical Imaging,the First People’s Hospital of Foshan,Guangdong 528000,China)

机构地区：[1]佛山市第一人民医院影像科,广东528000

出　　处：《放射学实践》2022年第11期1400-1404,共5页Radiologic Practice

基　　金：佛山市科技创新平台项目(FSOAA-KJ218-1301-0021);佛山市卫生健康局医学科研课题(20220079)。

摘　　要：目的:应用定量CT(QCT)测量内脏脂肪组织(VAT)面积与腹主动脉钙化(AAC)的相关性。方法:回顾性收集因腹部相关性疾病接受全腹部CT检查的患者357例。采用QCT测量腹部L2/3椎间隙水平VAT,根据VAT面积将所有患者分为VAT肥胖组(174例)和VAT正常组(183例);然后用Agatston方法测量腹主动脉钙化积分(AACS),根据AACS分为无AAC组(124例),轻度AAC组(73例),中度AAC组(60例)及重度AAC组(100例)。结果:VAT肥胖组的AACS明显高于VAT正常组(767.6±1473.7 vs 441.6±1067.8,P=0.018),且高血压及糖尿病的发病率也更高,差异有统计学意义(P值均<0.05)。采用Spearman分析显示年龄、男性、高血压及VAT面积与ACC严重程度呈正相关(R=0.690、0.107、0.34、0.448,P值均<0.05)。采用Logistic回归分析显示,只有年龄、高血压及VAT面积为AAC的独立危险因素(OR=2.903、2.264、1.996,P值均<0.05)。结论:腹腔内脏脂肪面积与腹主动脉钙化具有独立相关性,内脏脂肪的增多将可能导致ACC的发生或加重。Objective:To investigate the correlation between visceral adipose tissue(VAT) area and abdominal aortic calcification(AAC) based on quantitative computed tomography(QCT).Methods:357 patients who underwent whole abdominal CT examination were retrospectively reviewed.VAT was measured by QCT at L2/3 intervertebral space level,and AACS was measured according to Agatston method.They were divided into obesity group(n=174) and normal group(n=183) according to the VAT area,and non-AAC(n=124),mild(n=73),moderate(n=60) and severe AAC group(n=100).Results:The AACS of obesity group was significantly higher than that of normal group(767.6±1473.7 vs.441.6±1067.8,P=0.017),with significantly increased incidence of hypertension and diabetes(P<0.05).Spearman correlation showed that age,male,hypertension and VAT area were positively correlated with the severity of ACC(R=0.690,0.107,0.34,0.448,all P<0.05).Logistic regression analysis showed that age,hypertension and VAT area were independent risk factors for AACS(OR value=2.903,2.264,1.996,all P<0.05).Conclusion:VAT area significantly correlated with ACCS,and the increase of VAT may lead to the occurrence or aggravation of AAC.

关 键 词：定量CT 腹主动脉钙化 内脏脂肪 皮下脂肪 

分 类 号：R814.42[医药卫生—影像医学与核医学] R543.5[医药卫生—放射医学]