Insulin pumps in children-a systematic review  

作　　者：Mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Reem Elbeltagi 

机构地区：[1]Department of Pediatrics,Faculty of Medicine,Tanta University,Tanta 31511,Algharbia,Egypt [2]Department of Pediatrics,University Medical Center,King Abdulla Medical City,Arabian Gulf University,Manama 26671,Manama,Bahrain [3]Department of Pediatrics,University Medical Center,Dr.Sulaiman Al Habib Medical Group,Manama,Bahrain,Manama 26671,Manama,Bahrain [4]Medical Microbiology Section,Department of Pathology,Salmaniya Medical Complex,Ministry of Health,Kingdom of Bahrain,Manama 12,Manama,Bahrain [5]Department of Microbiology,Irish Royal College of Surgeon,Bahrain,Busaiteen 15503,Muharraq,Bahrain [6]Department of Chest Disease,Faculty of Medicine,Tanta University,Tanta 31527,Alghrabia,Egypt [7]Department of Chest Disease,University Medical Center,King Abdulla Medical City,Arabian Gulf University,Dr.Sulaiman Al Habib Medical Group,Manama 26671,Manama,Bahrain [8]Department of Medicine,The Royal College of Surgeons in Ireland-Bahrain,Busiateen 15503,Muharraq,Bahrain

出　　处：《World Journal of Clinical Pediatrics》2022年第6期463-484,共22页世界临床儿科杂志

摘　　要：BACKGROUND Insulin pump therapy is a real breakthrough in managing diabetes Mellitus,particularly in children. It can deliver a tiny amount of insulin and decreases the need for frequent needle injections. It also helps to maintain adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.Children are suitable candidates for pump therapy as they need a more freestyle and proper metabolic control to ensure adequate growth and development.Therefore, children and their caregivers should have proper education and training and understand the proper use of insulin pumps to achieve successful pump therapy. The pump therapy continuously improves to enhance its performance and increase its simulation of the human pancreas. Nonetheless, there is yet a long way to reach the desired goal.AIM To review discusses the history of pump development, its indications, types, proper use, special conditions that may enface the children and their families while using the pump, its general care,and its advantages and disadvantages.METHODS We conducted comprehensive literature searches of electronic databases until June 30, 2022,related to pump therapy in children and published in the English language.RESULTS We included 118 articles concerned with insulin pumps, 61 were reviews, systemic reviews, and meta-analyses, 47 were primary research studies with strong design, and ten were guidelines.CONCLUSION The insulin pump provides fewer needles and can provide very tiny insulin doses, a convenient and more flexible way to modify the needed insulin physiologically, like the human pancreas, and can offer adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.

关 键 词：Insulin pump CHILDREN Diabetes mellitus Keto-acidosis Continuous glucose monitoring Insulin therapy 

分 类 号：R725.8[医药卫生—儿科]