基于VOSviewer与CiteSpace的fMRI研究血管性认知障碍可视化分析  

Visual analysis of vascular cognitive impairment based on VOSviewer and CiteSpace by fMRI

作　　者：李晓陵[1] 高瑞雪 李昂[3] 崔璇 蔡丽娜 岳金换 曹丹娜[1] 张秦宏 LI Xiaoling;GAO Ruixue;LI Ang;CUI Xuan;CAI Lina;YUE Jinhuan;CAO Danna;ZHANG Qinhong(Department of CT&MR,the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;Graduate School of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;School of Public Health,Harbin Medical University,Harbin 150076,China;Department of Acupuncture and Massage,Shenzhen Jiuwei TCM Outpatient Department,Shenzhen 518000,China)

机构地区：[1]黑龙江中医药大学附属第一医院CT磁共振科,哈尔滨150040 [2]黑龙江中医药大学研究生院,哈尔滨150040 [3]哈尔滨医科大学公共卫生学院,哈尔滨150076 [4]深圳九味中医门诊部针灸推拿科,深圳518000

出　　处：《磁共振成像》2022年第11期99-104,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金面上项目(编号:82074537、81373714);黑龙江省自然科学基金联合引导项目(编号:LH2020H103、LH2021H101);深圳市龙华区科技创新项目(编号:2022010)。

摘　　要：目的 基于VOSviewer与CiteSpace分析功能磁共振成像(functional magnetic resonance imaging, fMRI)研究血管性认知障碍(vascular cognitive impairment, VCI)的现状、热点及趋势。材料与方法 检索中国知网(CNKI)、万方数据库(Wanfang)、维普数据库(VIP)建库至2022年收录的应用fMRI研究VCI的相关文献。采用NoteExpress去重并筛选文献,VOSviewer绘制核心作者密度视图,CiteSpace绘制机构合作网络图、关键词聚类图、关键词突现图及时间线图。结果 共纳入文献475篇,涉及1168位作者、148种期刊及212家机构。年度发文量呈增长趋势,作者合作团队较少,且各团队间无联系;发表期刊以中国科技核心期刊为主,尚未形成以某一机构为核心的合作团队,研究机构独立且分散。关键词聚类包括“认知功能、发病机制、海马、痴呆、脑微出血、核磁共振、早期诊断、海马损伤、高血压”9个聚类,关键词突现中“脑血流”为2018年开始并持续至今的突现词。结论 应用fMRI研究VCI的热度逐渐增加,热点集中于“认知功能、发病机制、海马、痴呆、脑微出血、核磁共振、早期诊断、海马损伤、高血压”方向,“脑血流”为该领域研究前沿。应用fMRI研究血管性认知功能障碍领域需注重作者、机构团队合作、把握研究热点和前沿,提高相关科研成果的产出。Objective: Based on VOSviewer and CiteSpace, the current status, hotspots and trends of functional magnetic resonance imaging(fMRI) research on vascular cognitive impairment(VCI) were analyzed. Materials and Methods: Relevant literatures on fMRI research on VCI included in the databases of CNKI, Wanfang and VIP until 2022 were retrieved. NoteExpress was used to deduplicate and screen the literature, VOSviewer drew the core author density view, and CiteSpace drew the institutional cooperation network graph,keyword clustering graph, keyword emergence graph and timeline graph. Results: A total of 475 papers were included, involving 1168 authors, 148 journals and 212 institutions. The annual publication volume is increasing, and there are few co-author teams, and there is no connection between the teams;the published journals are mainly Chinese science and technology core journals, and a cooperative team with a certain institution as the core has not yet been formed, and the research institutions are independent and scattered. Keyword clusters include "cognitive function, pathogenesis, hippocampus, dementia, cerebral microbleeds, MRI, early diagnosis, hippocampal injury,hypertension" 9 clusters, "cerebral blood flow" in the keyword emergence is the emergent word that started in 2018 and continues to this day. Conclusions: The popularity of fMRI research on VCI is gradually increasing. The hotspots focus on "cognitive function, pathogenesis,hippocampus, dementia, cerebral microbleeds, MRI, early diagnosis, hippocampal injury, hypertension", and "cerebral blood flow" is the research frontier in this field. In the field of fMRI research on vascular cognitive dysfunction, it is necessary to focus on institutional and team cooperation, grasp the research hotspots and frontiers, and improve the output of relevant scientific research results.

关 键 词：血管性认知障碍 轻度血管性认知障碍 血管性痴呆 可视化分析 功能磁共振成像 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.2[医药卫生—诊断学]