弥散磁共振成像在自身免疫性脑炎的研究进展  

Research progress of diffusion magnetic resonance imaging in autoimmune encephalitis

作　　者：李青芮 吴昆华[2] 龚霞蓉[2] 毕秋 李加奇 李秀 谢国清 LI Qingrui;WU Kunhua;GONG Xiarong;BI Qiu;WANG Jiaqi;LI Xiu;XIE Guoqing(College of Medicine,Kunming University of Science and Technology,Kunming 650000,China;Department of MRI,the First People's Hospital of Yunnan Province(the Affiliated Hospital of Kunming University of Science and Technology),Kunming 650032,China)

机构地区：[1]昆明理工大学医学院,昆明650000 [2]云南省第一人民医院(昆明理工大学附属医院)磁共振科,昆明650032

出　　处：《磁共振成像》2022年第11期133-136,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：云南省高层次卫生计生人才培养基金资助项目(编号:H-2019070)。

摘　　要：自身免疫性脑炎(autoimmune encephalitis, AE)是一类由自身免疫机制介导引起的脑炎,早期诊断和治疗有利于改善患者的预后。MRI检查在AE患者的检出、预后评估、疗效评价中起着重要作用,常规的MRI对AE病变的检出能力有限,弥散磁共振成像(diffusion magnetic resonance imaging, dMRI)是一种无创检测体内水分子运动的技术,它可敏感检出脑白质的微观病理变化,为AE的早期诊断、预后评估、疗效评价及病理生理机制的研究提供有效的信息。因此,笔者对常规MRI及dMRI技术在AE方面的研究现状及进展进行综述,并对未来研究方向进行展望。Autoimmune encephalitis(AE) is a kind of encephalitis caused by autoimmune mechanism mediated, early diagnosis and treatment is beneficial to the prognosis of patients with AE. MRI in the detection of patients with AE, prognostic evaluation, curative effect evaluation plays an important role. The detection ability of conventional MRI in AE is limited. Diffusion magnetic resonance imaging(dMRI) is a non-invasive imaging technique capable of characterizing the diffusion properties of water molecules in vivo and detecting microstructural changes in brain tissue. It provides new tools to investigate pathophysiological mechanism of AE. It is helpful for early diagnosis, evaluation of prognosis and curative effect. Therefore, this paper reviews the research status and progress of conventional MRI and dMRI technology in AE, and looks forward to the future research direction.

关 键 词：自身免疫性脑炎 边缘性脑炎 弥散磁共振成像 功能磁共振成像 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R512.3[医药卫生—诊断学]