影像组学在胰腺导管内乳头状黏液性肿瘤中的应用及研究进展  

Application and research progress of radiomics in intraductal papillary mucinous neoplasm of the pancreas

作　　者：赵钰莹 许万博 ZHAO Yuying;XU Wanbo(Binzhou Medical College,Yantai 264003,China;Department of Radiology,Qilu Hospital of Shandong University Dezhou Hospital,Dezhou 253011,China)

机构地区：[1]滨州医学院,烟台264003 [2]山东大学齐鲁医院德州医院放射科,德州253011

出　　处：《磁共振成像》2022年第11期154-156,168,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：山东省医药卫生科技发展计划项目(编号:202109010537);医学科研发展基金项目伦琴影像科研专项(编号:SD-202008-013)。

摘　　要：胰腺导管内乳头状黏液性肿瘤(intraductal papillary mucinous neoplasm of the pancreas, IPMN)是一种具有广泛疾病谱的潜在恶性肿瘤,目前普遍认为胰腺IPMN是胰腺癌的癌前病变,术前对其进行恶性程度评估判断具有重要意义。目前常用的传统影像学方法包括CT、 MRI、超声内镜(endoscopic ultrasonography, EUS)及正电子发射计算机断层显像(positron emission tomography-computed tomography, PET-CT)。影像组学通过高通量提取和定量分析影像特征为肿瘤定性提供了新方法,可对胰腺IPMN恶变潜能进行有效评估,现已逐步应用于胰腺IPMN恶性程度分级、预后预测及疗效评估等方面。本文就影像组学在胰腺IPMN恶性风险分层领域的发展及应用现状作一综述,并对未来发展做出展望。Intraductal papillary mucinous neoplasm(IPMN) of the pancreas is a potential malignant tumor with a broad spectrum of disease. It is generally believed that pancreatic IPMN is a precancerous lesion of pancreatic cancer, and it is of great significance to determine its malignancy degree before surgery. At present, the commonly used imaging methods include CT, MRI, endoscopic ultrasonography(EUS) and positron emission tomography-computed tomography(PET-CT). Radiomics provides a new method for tumor characterization through high-throughput extraction and quantitative analysis of image features, which can effectively evaluate the malignant potential of pancreatic IPMN. It has been gradually applied in pancreatic IPMN malignancy grading, efficacy evaluation and prognosis prediction. This article reviews the development and application of radiomics in the field of risk stratification of pancreatic IPMN malignancy, and prospects the future development.

关 键 词：胰腺导管内乳头状黏液性肿瘤 恶变潜能 影像组学 影像基因组学 计算机体层成像 磁共振成像 超声内镜 正电子发射计算机断层显像 人工智能 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.9[医药卫生—诊断学]