肌少症与骨质疏松的相关性研究进展  

Research progress on the relationship between sarcopenia and osteoporosis

作　　者：刘静[1] 段景宜 高海英[1] Liu Jing;Duan Jingyi;Gao Haiying(Department of General Medicine,the Second Affiliated Hospital of Dalian Medical University,Dalian 116023,China)

机构地区：[1]大连医科大学附属第二医院全科医学科,大连116023

出　　处：《中国临床保健杂志》2022年第5期593-599,共7页Chinese Journal of Clinical Healthcare

摘　　要：随着社会发展,老龄化逐渐加重,肌少症和骨质疏松症在老年人中广泛存在。肌少症和骨质疏松的共存现象被称为骨肌减少综合征。在未来几十年,老年人口增多,肌少症和骨质疏松症会大大增加个人和社会负担。同时患有这两种疾病的人群,其跌倒、骨折、住院率和死亡率都会大大增加。骨肌减少综合征的病因是多因素的,包括遗传、年龄、炎症和肥胖等。肌少症与骨质疏松症有共同的发病机制及干预治疗措施。该文旨在对肌少症及与骨质疏松症关系的研究背景、发病机制、危险因素以及治疗干预进行阐述,提高老年共病疾病预防能力。The coexistence of osteoporosis and sarcopenia has been recently considered widespread in the elderly, and some groups have recently considered the coexistence of osteoporosis and sarcopenia as a syndrome termed osteosarcopenia.With an aging population, the prevalence of both conditions is likely to increase substantially over the coming decades and is associated with a significant personal and societal burden.The sequelae for an individual suffering from both conditions together include a greater risk of falls, fractures, institutionalization, and mortality.The etiology of osteosarcopenia is multifactorial with several factors linking muscle and bone function, including genetics, age, inflammation, and obesity.In the current review, we outline the epidemiology, pathogenesis, and clinical consequences of osteosarcopenia and explore current and potential future management strategies to improve the prevention ability of senile comorbidities.

关 键 词：肌减少症 骨质疏松 危险因素 老年人 

分 类 号：R580[医药卫生—内分泌] R685[医药卫生—内科学]