基于通调三焦法运用三仁汤加减治疗湿热蕴脾型功能性便秘疗效观察  

Therapeutic effect of Sanren decoction with addition on functional constipation of dampness-heat stagnating in spleen type based on Tongtiao Sanjiao method

作　　者：张文秀 姜华 冯文哲 石鹏 ZHANG Wenxiu;JIANG Hua;FENG Wenzhe;SHI Peng(Shaanxi University of Traditional Chinese Medicine,Xianyang,Shaanxi 712000,China;Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang,Shaanxi 712000,China)

机构地区：[1]陕西中医药大学,陕西咸阳712000 [2]陕西中医药大学附属医院,陕西咸阳712000

出　　处：《检验医学与临床》2022年第22期3025-3027,3033,共4页Laboratory Medicine and Clinic

基　　金：国家自然科学基金项目(81973865);陕西省教育厅课题(17JK0214)。

摘　　要：目的观察三仁汤加减治疗湿热蕴脾型功能性便秘的临床疗效和安全性。方法选取于陕西中医药大学附属医院肛肠科门诊就诊的湿热蕴脾型功能性便秘患者70例为研究对象,采用随机数字表法分为治疗组和对照组,每组35例。对照组给予口服聚乙二醇4000散,10克/次,2次/天;治疗组给予口服三仁汤加减制成的中药汤剂,1剂/天,水煎,早晚温服。共治疗14 d,随访3个月。观察两组患者临床疗效,并比较两组患者粪便性状、排便难易、生存质量评分情况。结果在治疗14 d后,治疗组总有效率高于对照组(P<0.05)。治疗后,两组粪便性状、排便难易评分均降低(P<0.05),且治疗组较对照组降低更明显(P<0.05)。治疗后,两组身体不适、心理社会不适、担心和焦虑、满意度评分均降低(P<0.05),且治疗组较对照组降低更明显(P<0.05)。对照组患者服药期间出现1例腹痛、3例腹胀,治疗组服药期间未见不适。结论三仁汤加减治疗湿热蕴脾型功能性便秘临床疗效确切,且无不良反应。Objective To observe the clinical efficacy and safety of Sanren decoction with addition in the treatment of functional constipation of dampness-heat stagnating in spleen.Methods A total of 70 patients with functional constipation of dampness-heat stagnating in spleen admitted in the outpatient department of anorectal of Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine were selected as the research objects,and were divided into treatment group and control group by random number method,with 35 cases in each group.Control group was given oral PEG 4000 powder,10 g each time,twice a day.The treatment group was given the traditional Chinese medicine decoction made of Sanren decoction with addition orally,1 dose per day,pan fried,with lukewarm water in the morning and evening.All patients were treated for 14 days and followed up for 3 months.The clinical efficacy of the two groups were observed,and the stool characteristics,defecation difficulty and quality of life scores of the two groups were compared.Results After 14 days of treatment,the total effective rate in the treatment group was higher than that in the control group(P<0.05).After treatment,the stool characteristics and defecation difficulty score of the two groups decreased(P<0.05),and the treatment group decreased more significantly than the control group(P<0.05).After treatment,the scores of physical discomfort,psychosocial discomfort,worry and anxiety,and satisfaction in both groups decreased(P<0.05),and the treatment group decreased more significantly than the control group(P<0.05).There was one case of abdominal pain and three cases of abdominal distension in the control group,while no discomfort was found in the treatment group.Conclusion Sanren decoction with addition has a definite clinical effect on dampness-heat spleen-type functional constipation without adverse reactions.

关 键 词：通调三焦法 三仁汤加减 湿热蕴脾型功能性便秘 

分 类 号：R442.2[医药卫生—诊断学]