从鼻腔黏膜免疫探讨中药外用在流感预防中的应用与前景  

Explore the Application Prospect of External Chinese Medicine in the Prevention of Influenza from Nasal Mucosal Immunity

作　　者：董毅智 张悦 李皓月 郝鸣昭 黎晓蕾 赵静[1] DONG Yi-zhi;ZHANG Yue;LI Hao-yue;HAO Ming-zhao;LI Xiao-lei;ZHAO Jing(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;International Cooperation Department,China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of History of Medicine and Medical Literature,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]中国中医科学院国际合作处,北京100700 [3]中国中医科学院中国医史文献研究所,北京100700

出　　处：《南京中医药大学学报》2022年第11期1009-1014,共6页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：中国中医科学院科技创新工程中医临床基础学科创新团队项目(CI2021B003);中国中医科学院科技创新工程项目(C12021A00704-4)。

摘　　要：流行性感冒是由流感病毒引起的急性呼吸道传染病,曾多次引起世界性流感大流行并严重危害人类健康。鼻腔直接与外界联通,是流感病毒进入宿主的首要入口,其表面的鼻腔黏膜及相应免疫系统是抵抗病原体入侵机体的第一道防线,在流感预防中发挥着局部免疫并激发整体免疫的作用。从鼻腔黏膜免疫在流感预防中的作用,以及基于黏膜免疫的中药外用在预防流感的相关研究入手,探讨中药外用调节鼻腔黏膜免疫以预防流感的优势,以期为中药外用预防流感提供更多思路。Influenza is an acute respiratory infectious disease caused by influenza virus,which has caused many world influenza pandemics and seriously harmed human health.The nasal cavity is directly connected with the outside world,and is the main entrance of influenza virus into the host.The nasal mucosa and the corresponding immune system on its surface are the first line of defense against pathogen invasion,and play a role in local immunity and stimulate overall immunity in influenza prevention.This paper mainly discusses the advantages of regulating nasal mucosal immunity by external application of Chinese medicine to prevent influenza from the role of nasal mucosal immunity in influenza prevention and the related research of external traditional Chinese medicine based on mucosal immunity in influenza prevention,in order to provide more ideas for external application of Chinese medicine to prevent influenza.

关 键 词：鼻腔黏膜 免疫 流行性感冒 中药外用 

分 类 号：R285[医药卫生—中药学]