静电纺聚丙烯腈/聚苯胺复合材料的制备及电化学发光检测阿奇霉素  

Preparation of Electrospun PAN/PANI Composite Materials and Electrochemiluminescence Detection of Azithromycin

作　　者：王童飞 李学暖 李天昊 唐婷范[1] 覃丹凤 程昊[1,3] WANG Tongfei;LI Xuenuan;LI Tianhao;TANG Tingfan;QIN Danfeng;CHENG Hao(Guangxi Key Laboratory of Green Processing of Sugar Resources,College of Biological and Chemical Engineering,Guangxi University of Science and Technology,Liuzhou 545006;College of Medical,Guangxi University of Science and Technology,Liuzhou 545005;Province and Ministry Co-sponsored Collaborative Innovation Center of Sugarcane and Sugar Industry,Nanning 530004)

机构地区：[1]广西糖资源绿色加工重点实验室,广西科技大学生物与化学工程学院,广西柳州545006 [2]广西科技大学医学部,广西柳州545005 [3]蔗糖产业省部共建协同创新中心,广西南宁530004

出　　处：《分析科学学报》2022年第5期617-622,共6页Journal of Analytical Science

基　　金：国家自然科学基金(No.21968005);广西自然科学基金(桂科AD21220149);“八桂之光”访学研修计划(桂组通字[2021]64号)资助项目;广西科技大学博士启动基金(21Z06);广西高等学校高水平创新团队及卓越学者计划项目(桂教人[2014]7号)。

摘　　要：本文采用静电纺丝制备了一种聚丙烯腈/聚苯胺(PAN/PANI)复合材料。利用扫描电镜、能谱分析、X射线衍射等手段对制备的复合材料(CNFs)进行了表征。结果表明,所制备的PANI掺杂纳米纤维具交叉型3D纤维结构。复合材料元素主要由C元素、O元素和N元素构成。该CNFs材料可用于阿奇霉素的电化学发光检测,对阿奇霉素的线性检测范围为1.0×10^(-7)-9.0×10^(-5)μmol/L,线性相关系数R^(2)=0.999。检出限为5.9×10^(-9)μmol/L。在10、20、30μmol/L加标水平下的回收率为96.66%-102.59%,相对标准偏差小于5%(n=3)。该方法选择性好,灵敏度高,可用于阿奇霉素的检测。In this paper, a polyacrylonitrile(PAN)/polyaniline(PANI) composite material was prepared by electrospinning, and carbon fibers were further generated with PAN and PANI as the carbon source and nitrogen source.Then, a new type of string-shaped carbon nanofiber was prepared.SEM,EDS,XRD and XPS were used to detect and analyze the morphology, structure and elements of the composite material.The results show that the prepared nano-level PANI-doped nanofibers have a cross-type 3 D fiber structure.The composite material is mainly composed of C,O and N elements.The carbon nanofiber material can be used for the electrochemiluminescence detection of azithromycin and affords to high sensitivity.The detection range of modified electrodes for azithromycin is 1×10^(-7)-9×10^(-5)μmol/L,and the linear correlation coefficient(R^(2)) is 0.999.The limit of detection(LOD) is 5.9×10^(-9)μmol/L.The recovery of samples spiked with 10,20,and 30 μmol/L is within 96.66%-102.59%.Relative standard deviation(RSD,n=3) is below 5%.The method described in this paper provides good selectivity and high sensitivity for the detection of azithromycin.

关 键 词：碳纳米线纤维 聚苯胺 修饰电极 阿奇霉素 

分 类 号：O657.1[理学—分析化学]