抗痤疮药物模型研究进展  

Update of anti-acne pharmacological models

作　　者：李雪 丁鑫 汪奇 谭宁华[1] LI Xue;DING Xin;WANG Qi;TAN Ninghua(School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 211198,China)

机构地区：[1]中国药科大学中药学院,南京211198

出　　处：《中国麻风皮肤病杂志》2023年第1期45-50,共6页China Journal of Leprosy and Skin Diseases

基　　金：中国药科大学“双一流”高峰团队项目(编号:CPU2018GF05)。

摘　　要：痤疮发病机制复杂,其药理研究模型主要分为体内模型和体外模型,且针对不同的发病机制采用的药理模型也不相同。本文针对目前痤疮研究现状,综述了药理模型及其应用进展,以利于在实际应用中选择合适的模型,为治疗痤疮药物和化妆品研发提供参考。The pathogenesis of acne is complex,and its pharmacological research models are mainly divided into in vivo models and in vitro models,and different pharmacological models are used for different pathogenesis investigation.Based on the current status of acne research,the reported pharmacological models and their application progresses are reviewed in this paper,in order to facilitate the selection of suitable models for practical applications,and to provide a reference for the research and development of acne treatment drugs and cosmetics.

关 键 词：痤疮 体内药理模型 体外筛选模型 

分 类 号：R965.1[医药卫生—药理学]