人脑连接组学指导下的脑胶质瘤手术  

Glioma surgery guided by human brain connectomics

作　　者：张军霞[1] 尤永平[1] Junxia Zhang;Yongping You(Department of Neurosurgery,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院神经外科,南京市210029

出　　处：《中国肿瘤临床》2022年第21期1098-1102,共5页Chinese Journal of Clinical Oncology

基　　金：国家自然科学基金(编号:81974389)资助。

摘　　要：随着世界范围内脑计划研究的大范围开展,人脑连接组学研究得到了快速的发展。宏观尺度上的人脑连接组学主要采用脑成像和电生理技术,建立人脑网络的结构和功能连接模式及拓扑特征,进而揭示健康和疾病状态下人脑网络的组织规律和运行机制。目前人脑连接组学,作为大脑结构-功能精准分析的重要手段,在神经系统正常发育、神经系统疾病等领域中不断应用。本文对人脑连接组学的历史发展、研究进展进行综述,探讨人脑连接组学在脑胶质瘤领域的临床应用与潜在挑战。With the large-scale development of the human brain project globally,human brain connectomics has rapidly developed.Macroscopically,human brain connectomics mainly aims to establish structural and functional connection modes and topological characteristics of the human brain network via imaging and electrophysiological technology and reveal organizational and operational mechanisms of the human brain network in the health and disease states.Currently,human brain connectomics,as an important platform to accurately analyze brain structure and function,has been continuously applied in the fields of the normal development of the nervous system and diseases.This study summarizes the historical development and research progress of human brain connectomics and explores the clinical application and potential challenges of human brain connectomics in glioma.

关 键 词：人脑连接组学 脑胶质瘤 人脑网络 手术 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术] TN911.7[自动化与计算机技术—计算机科学与技术] R739.41[电子电信—通信与信息系统]