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作 者:Zhuo Liu Xi Cui Yubo Fan Zhou Li
机构地区:[1]Key Laboratory of Biomechanics and Mechanobiology,Ministry of Education,Beijing Advanced Innovation Center for Biomedical Engineering,School of Biological Science and Medical Engineering,School of Engineering Medicine,Beihang University,Beijing 100191,China [2]CAS Center for Excellence in Nanoscience,Beijing Key Laboratory of Micro-nano Energy and Sensor,Beijing Institute of Nanoenergy and Nanosystems,Chinese Academy of Sciences,Beijing 101400,China [3]School of Nanoscience and Technology,University of Chinese Academy of Sciences,Beijing 100049,China
出 处:《The Innovation》2022年第6期31-32,共2页创新(英文)
基 金:supported by the National Natural Science Foundation of China(82102231,T2125003,and 61875015);the China Postdoctoral Science Foundation(2020M680302 and 2021T140041);the Beijing Natural Science Foundation(JQ20038).
摘 要:Cells generate traction forces by interacting with the extracellular matrix(ECM)during migration,contraction,invasion,and spreading.Cell-traction forces(CTFs)are extremely small but have enormous biological effects.It has been discovered that CTFs serve a crucial role in regulating proliferation,differentiation,wound healing,morphogenesis,angiogenesis,inflammation,and tumor genesis by working together with biochemical signals to maintain a coherent framework for these processes.
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