健康人不同部位脉率变异性与心率变异性一致性分析  

Consistency analysis of pulse rate variability and heart rate variability in different parts of healthy people

作　　者：王斯涵 荆聪聪 蓝方 袁培 屠立平[1] 胡晓娟[1] 崔骥[1] 许家佗[1] WANG Si-han;JINGCong-cong;LAN Fang;YUAN Pei;TU Li-ping;HU Xiao-juan;CUI Ji;XU Jia-tuo(School of Basic Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Endocrinology,Shanghai Seventh People's Hospital,Shanghai 200137,China)

机构地区：[1]上海中医药大学基础医学院,上海201203 [2]上海市第七人民医院内分泌科,上海200137

出　　处：《中华中医药杂志》2022年第9期5083-5088,共6页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点研发计划中医药现代化研究重点专项(No.2017YFC1703301);国家自然科学基金项目(No.81873235,No.81973750,No.81904094);1226工程科技重点项目(No.BWS17J028);上海科委地方院校能力建设项目(No.21010504400)。

摘　　要：目的:通过对健康人多部位脉搏波与心电信号的同步采集,确立一致性较高的脉率变异性(PRV)采集部位与最短时长,为建立稳定高效的PRV采集分析方法提供实验依据。探索以往脉诊客观化指标与PRV的关系。方法:以心率变异性(HRV)与指端、桡动脉、肱动脉位置得到的PRV的18个指标作为观察指标,并用组内相关系数(ICC)来判断其一致性。用脉诊客观化指标与PRV做相关分析。结果:比较HRV与指端、桡动脉、肱动脉的PRV指标群发现,除triangular index和肱动脉SD2/SD1这一指标外,其他ICC均>0.95(P<0.01);指端、桡动脉的一致性均优于肱动脉所得结果。此外,在同一部位选取30 s和60 s时间长度的PRV,除VLF与VLF log一致性较差外,其余ICC均>0.7(P<0.01),有很高的一致性。结论:选取桡动脉、指端部位,30 s长度的脉搏波即可获得高效稳定的PRV,且与HRV一致性较高。PRV与以往应用的脉诊客观化指标一部分有相关性,并可以一定程度弥补以往缺失维度。Objective: To establish a consistent pulse rate variability(PRV) collection site and shortest duration by synchronizing the pulse wave and ECG signal collection from multiple parts of healthy people, and to provide an experimental basis for establishing a stable and efficient PRV collection and analysis method. To explore the relationship between the objective indicators of pulse diagnosis and PRV in the past. Methods: Heart rate variability(HRV) and 18 indexes of PRV obtained from the position of fingertip, radial artery and brachial artery were used as observation indexes, and the intraclass correlation coefficient(ICC) was used to judge the consistency. Correlation analysis was done with the objective index of pulse diagnosis and PRV.Results: Comparing HRV with the PRV index groups of the digit, radial artery and brachial artery, it was found that except for the triangle index and SD2/SD1 of radial artery, other results were all greater than 0.95(P<0.01);the consistency of the digit and radial artery was consistent. The results were better than those obtained by brachial artery. In addition, the PRV of 30 s and 60 s time lengths were selected at the same site, except for the poor consistency of VLF and VLF log, the ICC were all greater than 0.7(P<0.01), which had a high consistency. Conclusion: Selecting the radial artery and finger end, a pulse wave with a length of 30 s can obtain an efficient and stable PRV, and the consistency with HRV is high. PRV has a correlation with the objective indicators of pulse diagnosis used in the past, and can make up for the missing dimensions in the past to a certain extent.

关 键 词：脉搏波 脉诊客观化 脉率变异性 心率变异性 一致性分析 自主神经功能 

分 类 号：R241.1[医药卫生—中医诊断学]