针刺头维穴即刻脑激活效应的fMRI研究  

Study of f MRI on immediate brain activity of acupuncture at Touwei acupoint

作　　者：杨玉婵[1] 詹松华[1] 谭文莉[1] 成建明[1] 魏翔宇 徐春阳 龚志刚[1] 张敏[1] 杨辰瑶[1] 姜宏宁[1] YANG Yuchan;ZHAN Songhua;TAN Wenli;CHENG Jianming;WEI Xiangyu;XU Chunyang;GONG Zhigang;ZHANG Min;YANG Chenyao;JIANG Hongning(Department of Radiology,Shuguang Hospital Affiliated of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院放射科,上海201203 [2]上海中医药大学附属曙光医院针灸科,上海201203

出　　处：《中国中西医结合影像学杂志》2022年第6期532-534,共3页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：上海市科委“科技创新行动计划”医学创新研究专项(22Y11910600);上海中医药大学预算内项目(2021LK076)。

摘　　要：目的:采用低频振荡振幅(ALFF)静息态MRI技术探讨头针刺激两侧头维穴的即刻脑激活效应。方法:招募40例健康受试者,利用团队研发的3.0 T MRI兼容头颅柔性线圈,分别于针刺前、针刺即刻行BOLD-f MRI扫描。所有数据采用RESTplus预处理,分析针刺前、针刺即刻的激活脑区。将差异脑区的ALFF值与视觉模拟评分(VAS)行相关性分析。结果:针刺两侧头维穴即刻与针刺前相比,右侧颞下回ALFF值降低;右侧颞下回ALFF值与针感VAS呈正相关(r=0.557,P<0.05)。结论:基于3.0 T MRI兼容的针灸可视化平台,为进一步研究针刺头维穴治疗头部疾病的中枢作用机制提供了一种可行、客观的方法。Objective:To explore the immediate brain activity of the acupuncture stimulating effects of the Touwei acupoint with the amplitude of low frequency fluctuation(ALFF)resting state MRI analysis technique.Methods:Forty healthy subjects were collected and scanned with blood oxygen level-dependent(BOLD)f MRI before and immediately after acupuncture using the 3.0 T MRI compatible skull flexible coil developed by our team.All data were preprocessed with RESTplus to analyze the activated brain areas before and immediately after acupuncture.The correlation between ALFF value and visual analogue scale(VAS)score was analyzed.Results:After acupuncture on both sides of the Touwei acupoint,the ALFF value of the right inferior temporal gyrus decreased compared with that before acupuncture,and the ALFF value of the right inferior temporal gyrus was positively correlated with the acupuncture VAS score(r=0.557,P<0.05).Conclusions:3.0 T MRI compatible acupuncture visualization platform provides a feasible and objective method for further studying the central mechanism of the Touwei acupoint in the treatment of cerebral diseases.

关 键 词：功能磁共振成像 脑效应 低频振幅 头维穴 

分 类 号：R445.2[医药卫生—影像医学与核医学] R246[医药卫生—诊断学]